1. Taw qhia
Cordycepin hmoov CAS 73-03-0, tseem hu ua 3'-deoxyadenosine, yog thawj nucleoside tshuaj tua kab mob cais tawm ntawm cov kab mob. Cordycepin yog cov khoom xyaw tseem ceeb hauv Cordyceps militaris, thiab Cordyceps militaris yog tib hom kab mob uas tuaj yeem tsim ntau ntau ntawm 3'-Deoxyadenosine ntawm ntau tshaj 500 hom cordyceps.
2. Lub luag haujlwm tseem ceeb
2.1 Anti-tumor nyhuv
Cordycepin hmoov feem ntau inhibits kev tsim cov qog nqaij hlav hlwb RNA, thiab tom qab ntawd cuam tshuam cov synthesis ntawm cov qog nqaij hlav qog nqaij hlav, ua rau mob qog noj ntshav cell apoptosis. Nws tuaj yeem tso rau hauv lub hauv paus khub ntawm cov qog nqaij hlav DNA, khi rau pawg phosphate DNA, thiab cuam tshuam cov teeb liab hloov ntawm cov qog nqaij hlav cancer. Nws inhibits kev tsim cov hlab ntsha tshiab hauv cov txheej txheem ntawm cov qog nqaij hlav qog noj ntshav thiab txhawb nqa cov qog nqaij hlav cancer apoptosis.
2.2 Antibacterial, virus thiab tiv thaiv kab mob khaub thuas
Raws li ib tug natural nucleoside analog, cordycepin tuaj yeem cuam tshuam nrog kev rov ua dua thiab rov ua dua ntawm ntau yam kab mob. Qee qhov kev tshawb fawb tau pom tias cordycepin tuaj yeem cuam tshuam tus kab mob khaub thuas A hauv vitro thwmsim. Hauv kev siv cov tswv yim, noj cordyceps tuaj yeem tiv thaiv kab mob khaub thuas lossis txo lub sijhawm rov qab los; cordycepin tuaj yeem cuam tshuam cov synthesis ntawm RNA thaum lub sij hawm replication txheej txheem ntawm Western equine encephalitis tus kab mob, txo cov Virus khoom; cordycepin kuj muaj qee yam kev tiv thaiv HCV thiab tuaj yeem txhim kho cov tshuaj tiv thaiv kab mob ntawm interferon- thiab ribavirin, thiab inhibit qhov synthesis ntawm viral mRNA thiab polyadenylic acid; Qee qhov kev tshawb fawb kuj tau pom tias cordycepin muaj cov tshuaj tiv thaiv kab mob rau tib neeg tus kab mob herpes Virus, kab mob meningitis, thiab HIV-1 tus kab mob txhua tus muaj inhibitory thiab tua cov teebmeem. Cordycepin muaj cov kab mob dav dav, xws li inhibiting kev loj hlob ntawm cov kab mob pathogenic xws li Streptococcus, Bacillus pseudomallei, Bacillus anthracis, Bacillus hemorrhagic septicemia thiab Staphylococcus; Dermatophyte thiab lwm yam kab mob ntawm daim tawv nqaij fungi thiab Bacillus subtilis.
2.3 Anti-aging
Cordycepin tuaj yeem ua rau muaj kev ua haujlwm ntawm SOD enzymes hauv daim siab, inhibit qhov tsim ntawm superoxide tebchaw, thiab txhim khu kev ua haujlwm ntawm monoamine oxidase hauv lub hlwb, uas qhia tau hais tias cordycepin muaj kev tiv thaiv kev laus.
2.4 Txo cov ntshav lipids thiab anticoagulation
Cordycepin muaj cov nyhuv hypoglycemic thiab lipid-txo qis, thiab tseem muaj qee yam kev tswj xyuas cov kab mob ntsig txog ntshav qab zib thiab cov ntshav lipids, xws li ntshav qab zib thiab hyperlipidemia. Cordycepin muaj lipid-txo cov nyhuv. Nws cov txheej txheem ntawm kev ua: 1. tswj lub cev hnyav los ntawm kev tso tawm ntawm prolactin mediated los ntawm adenosine A1 receptors; 2. Hloov mus rau hauv cordycepin monophosphate, activates adenylate-activated protein kinase (AMPK), thiab txhawb Lipid decomposition, inhibit lipid synthesis; 3. Txo qhov kev qhia ntawm lipid droplet-txog noob caj noob ces Fsp27 thiab Perilipin1, yog li inhibiting fat droplet synthesis thiab inducing fat droplet degradation; 4. Txhawb kev hloov pauv cov ntaub so ntswg adipose xim av lossis cov ntaub so ntswg adipose dawb browning thiab ua kom lub zog noj.
2.5 Txhim kho kev ua haujlwm ntawm kev ua me nyuam
Cordyceps tau ntev tau txiav txim siab tias muaj cov nyhuv tonic rau txiv neej kev ua haujlwm ntawm kev ua haujlwm hauv Suav teb, thiab cordycepin, raws li cov khoom siv extraction ntawm Cordyceps, kuj tau lees paub hauv qhov no. Huang et al. tau pom thaum ntxov li 2011 tias cordycepin tuaj yeem txhawb PKA-cAMP teeb liab txoj hauv kev los ntawm adenosine receptors, induce Star protein qhia, txhawb steroid synthesis, thiab tom qab ntawd nce qib plasma testosterone. Tsis ntev los no, Kim et al. kuj pom tau hais tias cordycepin tuaj yeem nce qhov kev qhia ntawm mTORC1 hauv cov nas muaj hnub nyoog, txhawb nqa histone deacetylation, thiab nce qhov kev qhia ntawm spermatogenesis-related proteins thiab mRNAs, thaum kawg txhim kho phev motility hauv cov laus nas.
3. Daim ntawv thov
Cordycepin hmoov yog siv hauv kev kho mob thiab kev lag luam tshuaj.
4. Flow daim ntawv qhia
Matrix → pulverization → organic solvent extraction → centrifugation → sau cov supernatant → macroporous resin adsorption → purification → enrichment thiab sau cov qauv → elution → eluate distillation hauv qab txo siab → concentration → elution → crystallization → cordycepin
5. Tus Qauv Zoo
Raws li Enterprise Standard
Cov khoom | Specifications | Cov txiaj ntsig |
Qhov tshwm sim | Dawb hmoov | Dawb hmoov |
Particle loj | 100% dhau 80 mesh | Ua raws |
Poob rau ziab | Tsawg dua lossis sib npaug rau 2.0 feem pua | 1.72 feem pua |
Hnyav Hlau | Tsawg dua lossis sib npaug li 10ppm | <10ppm |
Pb | Tsawg dua lossis sib npaug li 2ppm | <2ppm |
Raws li | Tsawg dua lossis sib npaug li 1ppm | <1ppm |
Hg | Tsawg dua los yog sib npaug rau 1.0ppm | <1.0ppm |
Cd | Tsawg dua lossis sib npaug rau 0.5ppm | <0.5ppm |
Tag Nrho Phaj suav | Tsawg dua lossis sib npaug li 1000cfu / g | <1000cfu/g |
Poov & Pwm | Tsawg dua lossis sib npaug li 100cfu / g | <100cfu/g |
E. Coli. | Tsis zoo | Tsis pom |
Salmonella | Tsis zoo | Tsis pom |
Kev ntsuam xyuas (HPLC) | Ntau dua lossis sib npaug rau 98.0 feem pua | 9 8.58 tzs |
6. Txoj kev tsom xam
MOA muaj nyob rau thaum thov.
7. Reference Spectrum
8. Kev ruaj ntseg thiab kev nyab xeeb
Kev ruaj ntseg:
Nyob ruaj khov nyob rau hauv cov xwm txheej zoo (chav kub). Cov Ntaub Ntawv Kev ruaj ntseg muaj nyob rau ntawm koj qhov kev thov.
Kev nyab xeeb:
Raws li GARS (Feem ntau Pom Zoo Raws Li Kev Nyab Xeeb) Daim Ntawv Ceeb Toom ntawm Teb Chaws Asmeskas, nws muaj kev nyab xeeb rau tib neeg siv.
9. Cov neeg siv lus pom
10. Peb Daim Ntawv Pov Thawj
11. Peb Cov Neeg Siv Khoom
12. Exhibition
Cim npe nrov: cordycepin hmoov cas 73-03-0, manufacturers, lwm tus neeg, Hoobkas, lag luam wholesale, yuav, nqe, zoo tshaj plaws, tej, kev muag khoom
