Licorice Extract Glabridin CAS 59870-68-7

1. Taw qhiaon

Glabridin (CAS No. 59870-68-7) yog ib qho isoflavonoid nrog cov mis mos molecular C20H20O4. Nws yog ib tug whitening neeg sawv cev muab rho tawm los ntawm licorice (Glycyrrhiza glabra) hauv paus. Nws yog insoluble hauv dej, soluble hauv ethanol thiab propylene glycol.

2. Txoj kev rho tawm

Glabridin feem ntau yog siv los ua ib feem ntawm G. Glabra crude extract, tsis yog ib qho tshuaj lom neeg. Yog li txoj kev rho tawm yog qhov tseem ceeb. Txij li feem ntau glabridin siv rau hauv kev lag luam tshuaj pleev ib ce, khoom noj khoom haus thiab tshuaj, cov kuab tshuaj yuav tsum tsis muaj tshuaj lom thiab cov kev siv yuav tsum yog ib puag ncig zoo. Peb txais cov licorice pov tseg residue ua raw khoom. Cov khoom tiav ntawm glabridin yog tau los ntawm cov txheej txheem ntawm extraction, impurity tshem tawm thiab adsorption. Cov txheej txheem yog qhov zoo hauv qhov ntawd: licorice cov khoom pov tseg yog rov siv dua thiab tus nqi ntawm glabridin tuaj yeem txo qis ntau; cov kuab tshuaj sib xyaw yog siv rau kev rho tawm kom cov extraction tus nqi ntawm glabridin yog maximized thiab cov zis yog nce; chav-kub extraction yog saws, thiab yog li ntawd cov txheej txheem ntau lawm yog yooj yim rau kev khiav lag luam, tshem tawm impurities tsawg, purity ntawm glabridin yog siab, hnyav volatility yog txo, kev ruaj ntseg nyob rau hauv ntau lawm yog zoo dua thiab tus nqi txo.

3. Kev ua haujlwm

3.1. Anti-oxidation thiab melanogenesis inhibitory

Txoj hauv kev ntawm melanin synthesis yog qhia hauv daim duab hauv qab no. Muaj peb lub ntsiab enzymes koom nrog cov synthesis ntawm eumelanin. Tyrosinase yog lub luag haujlwm tseem ceeb hauv kev tsim cov tshuaj melanin.

Glabridin muaj qhov cuam tshuam zoo heev ntawm kev ua haujlwm ntawm tyrosinase. Daim duab hauv qab no yog daim duab simulation. Glabridin tuaj yeem tsim ib daim ntawv cog lus hydrogen nrog lub chaw nquag ntawm tyrosinase thiab ruaj khov hauv tyrosine. Ntawm qhov nkag ntawm lub enzyme, cov khoom siv raw rau kev sib txuas ntawm melanin tsis tuaj yeem nkag mus, thiab cov khoom ua tiav ntawm melanin tsis tuaj yeem tsim, uas txo cov khoom melanin.

Tsis tas li ntawd, Glabridin tuaj yeem ua ib txhij ntawm tryosinase, dopachrome, tautomerase, DHICA oxidase thiab -MSH melanin.

3.2. Brightening thiab anti-redness

US AMA Laboratories, INC. tau ua ib qho kev sim los ua pov thawj qhov ci ntsa iab thiab tiv thaiv liab ntawm Glabridin. Peb tuaj yeem pom cov txiaj ntsig hauv cov duab hauv qab no:

Tus naj npawb ntawm cov kev kawm: 2

Cov qauv kuaj: 0.04 feem pua ​​glabridin 90 feem pua ​​hauv 1,3-butanediol tov

Kev Siv: 1ml ib zaug thiab 2 ml (1 lub raj mis) ib hnub, tag nrho 56 hnub.

Coj cov duab daws teeb meem siab rau hnub 0, 7, 14, 28 thiab 56 raws, thiab tshuaj xyuas L* thiab A* qhov tseem ceeb nrog kev tshuaj ntsuam software.

Hnub 0 Hnub 7 Hnub 14 Hnub 28 Hnub 56

Glabridin muaj qhov tseem ceeb brightening, whitenign thiab anti-redness los.

Tom qab 56 hnub, L * tus nqi (tawv nqaij lightness) tau txhim kho los ntawm qhov nruab nrab ntawm 60.87 feem pua, thiab A* tus nqi cuam tshuam nrog lub ntsej muag liab poob los ntawm 75.0 feem pua.

3.3. Inhibits inflammatory yam tseem ceeb thiab fights UV rays

Qee cov kws tshawb fawb tau kawm txog glabridin liposomes los txhim kho erythema thiab kab mob ntawm daim tawv nqaij los ntawm lub teeb ultraviolet los ntawm inhibiting inflammatory yam. Glycyrrhizin liposomes tuaj yeem siv los txhim kho bioavailability nrog tsawg cytotoxicity thiab zoo dua melanin inhibitory nyhuv, uas tuaj yeem txo cov kev qhia ntawm inflammatory cytokines, interleukin -6 thiab interleukin -10. Yog li ntawd, nws tuaj yeem siv los ua cov tshuaj pleev ib ce los tua cov tawv nqaij puas tsuaj los ntawm ultraviolet hluav taws xob los ntawm inhibiting o, uas tuaj yeem muab qee cov tswv yim rau kev tshawb fawb ntawm cov khoom siv tshuaj dawb thiab tshuaj pleev thaiv hnub.

4. Cov ntawv thov

Tam sim no, licorice extract glabridin feem ntau yog siv rau hauv cov khoom siv tshuaj pleev ib ce high-end.

Kev Siv Tshuaj

Glabridin {{0}}:0.03 feem pua ​​~ 0.1 feem pua

Glabridin {{0}}:0.015 feem pua ​​~ 0.05

5. Cov Qauv Zoo ntawm Glabridin

Raws li QB/T 4951-2016

6. Cov lus qhia tshwj xeeb

7. Kev Tshawb Fawb Txog Kev Nyab Xeeb thiab Kev Nyab Xeeb

Cov kev tshawb fawb qhia tias kev ruaj ntseg ntawm glabridin nyob rau hauv licorice extract nyob ntawm illumination, kub, pH, hnyav, av noo thiab oxidant, uas illumination yog lub ntsiab tseem ceeb. Kev sib cuam tshuam ntawm kub thiab pH, illumination thiab pH, thiab kub thiab av noo nce tus nqi degradation ntawm glabridin. Yuav kom txo qis degradation, peb xav tias cov ntshiab glabridin thiab licorice extract yuav tsum muab cia rau hauv qhov tsaus ntuj, qhuav thiab airtight ib puag ncig. Cov kuab tshuaj uas tsim nyog tau pom zoo, yuav tsum zam qhov kub thiab txias, thiab pH yuav tsum tau ua tib zoo tswj hauv cov txheej txheem cais. Txawm li cas los xij, nws tsim nyog sau cia tias oxygen tuaj yeem txhawb nqa ntau yam kev cuam tshuam. Cov kev tshawb fawb tau pom tias qhov cuam tshuam ncaj qha ntawm cov pa oxygen ntawm kev ruaj ntseg ntawm glabridin tsis muaj zog, tab sis kev sib cuam tshuam nws yuav ua rau lwm yam tseem yuav tsum tau tshawb xyuas. Yog li ntawd lub xub ntiag ntawm cov pa oxygen yuav tsum raug zam ob qho tib si hauv kev khaws cia thiab kev sib cais ntawm glabridin kom txo nws cov degradation.

Peb Glabridin yog cov nroj tsuag ntuj tsim. Cov khoom no tau raug cais los ntawm FDA raws li cov khoom siv tsis muaj tshuaj lom. Nws kuj tau pom zoo raws li ib qho ntawm cov khoom xyaw zoo tshaj plaws thiab muaj txiaj ntsig zoo tshaj plaws thoob ntiaj teb.

8. Siv Chromotogram ntawm Glabridin

9. Cov lus teb rau cov neeg siv khoom

10. Peb Daim Ntawv Pov Thawj

11. Cov neeg siv khoom loj

12. Exhibition

Cim npe nrov: licorice extract glabridin cas 59870-68-7, manufacturers, lwm tus neeg, Hoobkas, lag luam wholesale, yuav, nqe, zoo tshaj plaws, tej, kev muag khoom