Phloretin hmoov 60-82-2

1. Taw qhia

Phloretin hmoov yog muab rho tawm los ntawm tev thiab cag ntoo ntawm cov txiv hmab txiv ntoo muaj kua xws li txiv apples thiab pears. Nws yog ib hom polyphenol, uas muaj zog tiv thaiv oxidation thiab lub teeb kev tiv thaiv muaj peev xwm thiab nws tau siv nyob rau hauv ntau yam khoom kom zoo nkauj. Cov phloretin hmoov uas ua los ntawm Kono yog los ntawm cov kua tev zoo thiab nws tsis muaj tshuaj tua kab thiab kab mob. Nws yog siab purity thiab zoo solubility.

2. Lub luag haujlwm tseem ceeb

2.1. Antioxidant nyhuv.

Nrog rau kev txhim kho ntawm tib neeg lub neej zoo thiab kev laus thoob ntiaj teb, ntau thiab ntau tus neeg raug kev txom nyem los ntawm cov teeb meem ntawm daim tawv nqaij laus, thiab cov tshuaj pleev ib ce thiab cov khoom siv kho mob nrog kev tiv thaiv kev laus tau dhau los ua qhov tseem ceeb ntawm kev lag luam tu tus kheej niaj hnub no. Cov dawb radical txoj kev xav ntawm kev laus yog dav lees paub, thiab tam sim no lub ntsiab txhais ntawm kev laus ntawm daim tawv nqaij yog kev siv cov tshuaj antioxidants sab nraud los tiv thaiv thiab txo cov kev hloov dawb radical. Cov kev tshawb fawb tau pom tias phenolic hydroxyl pawg nyob rau hauv cov qauv ntawm ntuj flavonoids tuaj yeem hnov ​​​​mob dawb radicals los tsim cov semi-quinone radicals ruaj khov, yog li inhibiting qhov pib ntawm lipid peroxidation thiab tshem tawm cov dawb radical saw cov tshuaj tiv thaiv. Phloretin yog dihydrochalcone flavonoid nrog plaub pawg phenolic hydroxyl, thiab nws cov qauv tshwj xeeb txiav txim siab nws cov haujlwm muaj zog antioxidant. Cov kev sim hauv vitro tau pom tias phloretin muaj peev xwm inhibit mitochondrial lipid peroxidation thiab tshem tawm DPPH radicals thiab ABTS radicals. Nws tau pom tias cov cag ntoo muaj zog antioxidant, thiab cov tshuaj tua kab mob antioxidant ntawm 10.30 mg / L rau roj thiab roj tuaj yeem tshem tawm cov dawb radicals hauv daim tawv nqaij. Cov nyhuv antioxidant ntawm cov cag ntoo tsis yog ntawm nws tus kheej xwb, tab sis kuj tuaj yeem ua ke nrog cov tshuaj antioxidants uas twb muaj lawm los txhim kho cov nyhuv antioxidant.

2.2. Nyob rau hauv xyoo tas los no, qhov tshwm sim ntawm cov tawv nqaij rhiab heev tau nce, thiab kev lag luam tshuaj pleev ib ce tau dhau los ua kev txhawj xeeb txog cov tawv nqaij rhiab heev. Cov kab mob ntawm daim tawv nqaij xws li seborrheic dermatitis, pob txuv, perioral dermatitis, thiab atopic dermatitis feem ntau cuam tshuam nrog cov tawv nqaij rhiab heev. Raws li kev txheeb cais tsis tiav, ntau tshaj li ib feem peb ntawm cov neeg nyob hauv tsev thiab txawv teb chaws tau raug kev txom nyem los ntawm kev tsis haum tshuaj nyob rau hauv lawv lub neej, thiab cov poj niam uas muaj cov tawv nqaij rhiab heev hauv ntau thaj tsam suav nrog ntau dua 50 feem pua ​​​​ntawm cov pej xeem ib txwm muaj. Kev tshawb fawb qhia tau hais tias cov tawv nqaij rhiab heev yog tshwm sim los ntawm kev ua haujlwm tsis zoo ntawm daim tawv nqaij ua haujlwm, ua rau cov hlab ntsha muaj zog thiab ua kom lub cev tsis muaj zog. Thaum daim tawv nqaij teeb meem yog impaired, permeability ntawm irritant nce thiab irritant induces tso tawm pro-inflammatory thiab chemotactic yam los ntawm txawv hlwb, uas tswj kev loj hlob ntawm kev tiv thaiv thiab o, yog li txhawb kev loj hlob ntawm cov tawv nqaij rhiab heev. Yog li ntawd, inhibition ntawm zus tau tej cov inflammatory thiab chemokines yuav inhibit los yog txo cov kev puas tsuaj los ntawm daim tawv nqaij thaum lub sij hawm inflammatory teb. Cov kev tshawb fawb hauv vitro tau pom tias phloretin muaj peev xwm inhibit qhov tsim ntawm inflammatory yam, chemokines thiab sib txawv yam thiab muaj qee qhov kev tiv thaiv kab mob. Hauv kev tshawb fawb vivo kuj tau pom tias phloretin muaj cov tshuaj tua kab mob antioxidant thiab tiv thaiv kab mob. Nws cov tshuaj tiv thaiv kab mob hauv vitro thiab hauv vivo qhia tias nws muaj peev xwm siv tau rau hauv kev ua xua rau cov khoom tu tawv nqaij. Tsis tas li ntawd, cov tshuaj niaj hnub no tau qhia tias qhov tseem ceeb cuam tshuam nrog pob txuv pathogenesis thiab o feem ntau tsis cais. phloretin tuaj yeem siv tshuaj pleev ib ce los tiv thaiv kev nkag ntawm glycoconjugates rau hauv cov hlwb epidermal, inhibit qhov kev tsim tawm ntawm dermatoglandular secretion, thiab kho pob txuv vulgaris, thaum nkag mus rau sab hauv ntawm cov hlwb tuaj yeem txo qis COX-2 txhawb kev ua haujlwm thiab inhibit prostate E2 ntau lawm. Nws kuj nkag mus rau hauv lub cell kom txo tau COX-2 txhawb kev ua haujlwm, inhibit prostate E2 ntau lawm, thiab txo qhov mob ntawm daim tawv nqaij pob txuv. Hauv kev xaus, phloretin tsis tau tsuas yog cov nyhuv antioxidant tab sis kuj muaj kev tiv thaiv kev ua haujlwm, uas muaj ntau yam ntawm daim ntawv thov kev cia siab hauv pob txuv tshuaj pleev ib ce thiab kev tsis haum tshuaj pleev ib ce.

2.3 Antibacterial nyhuv

Cov tshuaj tua kab mob yog ib qho tseem ceeb hauv cov tshuaj pleev ib ce thiab yog ib qho tseem ceeb ntawm kev nyab xeeb ntawm cov tshuaj pleev ib ce. Tam sim no, hom tshuaj pleev ib ce tso cai khaws cia raug txo qis thiab siv cov tshuaj pleev ib ce uas muaj ntau ntau, thiab kev tsim cov tshuaj tua kab mob tshiab thiab nyab xeeb tau dhau los ua ib qho kev sib tw tseem ceeb rau kev tsim kho kom zoo nkauj.Phloretin yog flavonoid compound nrog cov tshuaj tua kab mob.

Nws tau pom tias phloretin muaj zog inhibitory nyhuv ntawm Gram-zoo kab mob, tshwj xeeb tshaj yog nyob rau Staphylococcus aureus, Listeria monocytogenes thiab Salmonella typhimurium. Ntxiv nrog rau nws cov tshuaj tua kab mob tiv thaiv cov kab mob pathogenic, phloretin kuj tseem muaj kev cuam tshuam rau cov kab mob ntawm daim tawv nqaij. Kev loj hlob ntawm cov kab mob ntawm daim tawv nqaij xws li Propionibacterium acnes tuaj yeem ua rau muaj teeb meem ntawm daim tawv nqaij xws li pob txuv. Cov txiaj ntsig ntawm kev sim tshuaj ntsuam xyuas kuj tau pom qhov txo qis hauv cov taub hau dawb, taub hau dub, pob ntxau thiab sebum tso tawm tom qab 4 lub lis piam ntawm kev siv phloretin, qhia tias phloretin muaj peev xwm txo tau pob txuv. Phloretin's inhibitory nyhuv ntawm cov kab mob yog, ntawm ib sab, ua rau cov enzymes sab hauv thiab cov kab mob protein ntawm cov kab mob, cuam tshuam rau lawv lub zog metabolism thiab kho oxidative kev puas tsuaj rau cov kab mob loj hlob, thiab ntawm qhov tod tes, cuam tshuam nrog cov protein nyob hauv. synthesis ntawm cov hlwb. Ntawm qhov tod tes, phloretin cuam tshuam nrog synthesis ntawm cov proteins hauv lub cell, ua rau muaj kev cuam tshuam ntawm intracellular metabolism thiab thaum kawg ua rau cov kab mob tuag.

2.4. Whitening nyhuv

Tam sim no, kev txhim kho ntawm cov tshuaj ntxuav hniav dawb yog dominated los ntawm inhibition ntawm tyrosinase kev ua. Nws tau pom tias phloretin muaj peev xwm inhibit tyrosinase kev ua haujlwm. Nws tau pom tias 0. 3% phloretin inhibited tyrosinase mus txog 98. 2 feem pua. Qhov inhibition ntawm tyrosinase yog qhov zoo tshaj plaws ntawm cov tshuaj ntxuav hniav dawb (triglyceride thiab arbutin), thiab nws tau pom ntxiv tias kev sib xyaw ntawm phloretin nrog cov tyrosinase inhibitors tuaj yeem txhim kho nws qhov inhibition npaum li cas, zoo li 100 feem pua ​​inhibition.

2.5 Moisturizing nyhuv

Cov tawv nqaij noj qab haus huv yuav tsum tswj cov dej noo ntawm stratum corneum ntawm 10 feem pua ​​​​thiab 30 feem pua ​​​​, thaum qis dua 10 feem pua ​​​​ntawm daim tawv nqaij yuav tshwm sim qhuav, poob elasticity, wrinkle, thiab ua kom cov tawv nqaij laus. Yog li ntawd, cov dej noo yog qhov tseem ceeb rau kev noj qab haus huv ntawm daim tawv nqaij, thiab dej tuav thiab moisturization tau dhau los ua qhov tseem ceeb tshaj plaws ntawm cov neeg siv khoom ntawm kev ua tau zoo ntawm cov tshuaj pleev ib ce. Phloretin molecules muaj plaub pawg hydroxyl uas tuaj yeem tsim hydrogen bonds nrog dej molecules thiab nqus dej, uas muaj peev xwm moisturizing nyhuv.

2.6 Anti-hais plaub hau nyhuv

Nrog rau kev nrawm nrawm ntawm lub neej thiab kev ntxhov siab ntau ntxiv hauv tib neeg lub neej, cov teeb meem plaub hau feem ntau tshwm sim, yog li cov khoom siv los tiv thaiv plaub hau yog nrov ntawm cov neeg siv khoom. Soybean lipoxygenase yog ib qho ntawm cov enzymes tseem ceeb hauv cov txheej txheem ntawm lipid oxidation, thiab tib lub sijhawm nws koom nrog cov txheej txheem ntawm cov tshuaj tiv thaiv kab mob hauv daim tawv nqaij, uas yog ib qho tseem ceeb enzymes cuam tshuam rau cov plaub hau. Cov kev tshawb fawb tau pom tias phloretin tuaj yeem cuam tshuam cov taum lipoxygenase kev ua haujlwm, yog li txo cov plaub hau poob vim kev laus ntxov ntxov, qhia tias phloretin muaj peev xwm tiv thaiv plaub hau poob thiab tuaj yeem muab ntxiv rau cov tshuaj zawv plaub hau thiab cov tshuaj pleev ib ce ua cov tshuaj tiv thaiv plaub hau.

3. Cov ntawv thov

Raws li ib tug natural cosmetic additive, phloretin hmoov yog feem ntau siv nyob rau hauv lub ntsej muag lub ntsej muag, tshuaj pleev ib ce, tshuaj pleev ib ce thiab essences.Nws kuj yog siv nyob rau hauv cov zaub mov, tshuaj, khoom noj qab haus huv thiab ntau yam teb.

4. Flow Chart

5. Tus Qauv Zoo

Raws li GB1886.261-2016

6. Txoj kev tsom xam

MOA muaj nyob rau thaum thov.

7. Siv Chromatogram

8. Kev ruaj ntseg thiab kev nyab xeeb

Kev ruaj ntseg:
Nyob ruaj khov nyob rau hauv cov xwm txheej zoo (chav kub). Cov Ntaub Ntawv Kev ruaj ntseg muaj nyob rau ntawm koj qhov kev thov.
Kev nyab xeeb:

Nws muaj kev nyab xeeb rau kev siv hauv vitro.

9. Cov neeg siv lus pom

10. Peb Daim Ntawv Pov Thawj

11.Peb cov neeg muas zaub

12. Exhibitions

Cim npe nrov: phloretin hmoov 60-82-2, manufacturers, lwm tus neeg, Hoobkas, lag luam wholesale, yuav, nqe, zoo tshaj plaws, tej, kev muag khoom