Kono Chem Co., Ltd. yog ib qho zoo tshaj plaws manufacturers thiab lwm tus neeg ntawm -lipoic acid 1077-28-7 nyob rau hauv Suav teb. Peb sov siab txais tos koj rau cov lag luam wholesale bulk-lipoic acid 1077-28-7 muag ntawm no los ntawm peb lub hoobkas. Tag nrho cov khoom siv tshuaj muaj txiaj ntsig zoo thiab cov nqi sib tw.
1. Taw qhia
-Lipoic acid (ALA), tseem hu ua DL-lipoic acid nyob rau hauv kev lag luam scenarios, yog ib tug tshwm sim organosulfur compound. Nws raug cais raws li "universal antioxidant" vim nws qhov tshwj xeeb dual solubility nyob rau hauv ob qho tib si lipids thiab dej, tso cai rau nws nkag mus rau tag nrho cov cellular compartments nrog rau cytoplasm, mitochondria, thiab cell membranes.
Chemically, nws yog ib tug puab disulfide compound tsim los ntawm ib tug disulfide daim ntawv cog lus ntawm lub 6th thiab 8th carbon atoms ntawm nws cov qauv. Kev lag luam muaj nyob hauv -lipoic acid feem ntau yog ib qho kev sib xyaw ua ke ntawm haiv neeg sib tw (DL- daim ntawv), suav nrog qhov sib npaug ntawm R-lipoic acid (ib txwm tshwm sim hauv daim ntawv) thiab S-lipoic acid. Thaum txo qis hauv vivo lossis hauv cov tshuaj tiv thaiv, nws daim ntawv cog lus disulfide tawg rau hauv daim ntawv dihydrolipoic acid (DHLA), ib daim ntawv txo nrog kev ua kom muaj zog lom neeg.
2. Muaj nuj nqi
2.1.Muaj peev xwm Antioxidant Activity.Raws li ob- lub hom phiaj antioxidant, -lipoic acid ncaj qha scavenges ntau yam dawb radicals (xws li hydroxyl radicals thiab superoxide anions) kom txo oxidative kev nyuaj siab rau hlwb. Nws daim ntawv txo qis, dihydrolipoic acid, nthuav tawm txawm tias muaj zog antioxidant muaj peev xwm thiab tuaj yeem rov tsim dua lwm cov antioxidants tseem ceeb xws li vitamin C, glutathione, thiab vitamin E, tsim kom muaj kev sib koom ua ke antioxidant hauv lub cev.
2.2.Metabolic Regulation.Nws ua hauj lwm raws li ib tug tseem ceeb cofactor rau mitochondrial enzymes (xws li, pyruvate dehydrogenase complex) thiab koom nyob rau hauv lub tricarboxylic acid voj voog. Los ntawm kev txhim kho cellular qabzib uptake thiab siv efficiency, nws txhawb kev hloov cov piam thaj rau hauv lub zog (ATP), pab kom stabilize cov ntshav qab zib theem thiab txhawb ib txwm metabolic muaj nuj nqi.
3. Daim ntawv thov
3.1 Pharmaceutical Field
Nws yog dav siv nyob rau hauv cov tshuaj formulations rau kev kho mob ntshav qab zib peripheral neuropathy, raws li nws txhim kho cov hlab ntsha conduction thiab relieves cov tsos mob xws li loog loog thiab tingling. Tsis tas li ntawd, nws yog ib qho tshuaj nruab nrab rau kev tsim cov tshuaj tsom rau kab mob siab ntev thiab lwm yam kev ntxhov siab oxidative- ntsig txog kab mob.
3.2 Cov Khoom Muag Khoom Noj Kho Mob
Raws li cov khoom xyaw tseem ceeb hauv cov khoom noj khoom haus, nws yog muag rau kev txhawb nqa antioxidant, kev tiv thaiv kab mob, thiab kev kho mob metabolic. Nws kuj tseem ntxiv rau cov khoom noj uas muaj txiaj ntsig (xws li, dej qab zib, khoom noj qab haus huv) kom txhawb nqa lawv cov khoom noj muaj txiaj ntsig thiab txiaj ntsig kev noj qab haus huv.
3.3 Cosmetic Field
Muab tso rau hauv siab- kawg los tiv thaiv- cov khoom tu tawv nqaij laus (nrog qib pom zoo ntxiv ntawm 0.1%-1.0%), nws tshem tawm cov dawb radicals, txhim kho daim tawv nqaij dullness, txo cov kab zoo, thiab txhim kho daim tawv nqaij ua haujlwm. Nws dual solubility tso cai rau nws nkag mus tob rau hauv daim tawv nqaij rau kev tiv thaiv.
4.Quality Standard
|
Purity |
Pharmaceutical/Healthcare Qib (USP Standard): 99.0% -101.0%, Tag nrho cov impurities Tsawg dua lossis sib npaug li 0.5% -2.0% Qib Reagent: Ntau dua lossis sib npaug li 98.0% (HPLC Test) |
|
Qhov tsos thiab tus cwj pwm |
daj ntseg daj mus rau daj crystalline hmoov |
|
Melting Point |
60-64 degree |
|
Kev sib hloov tshwj xeeb |
1℃~ +1 degree |
|
Impurities thiab residues |
Cov Hlau Hnyav: Tag Nrho Tsawg dua lossis sib npaug rau 10ppm (Pb Tsawg dua lossis sib npaug rau 3ppm, Cd Tsawg dua lossis sib npaug rau 1ppm, Hg Tsawg dua lossis sib npaug rau 0.1ppm) Poob rau ziab Tsawg dua lossis sib npaug li 0.5%, Ignition Residue Tsawg dua lossis sib npaug li 0.1% Residual Solvents: Cyclohexane Tsawg dua lossis sib npaug rau 1000ppm, Ethyl Acetate Tsawg dua lossis sib npaug rau 250ppm, Toluene Tsawg dua lossis sib npaug rau 50ppm |
|
Cov kab mob |
Tag Nrho Aerobic Microbial suav Tsawg dua lossis sib npaug rau 1000CFU / g, Pwm thiab Pwm Tsawg dua lossis sib npaug rau 100CFU / g, Cov kab mob tsis pom |
5.Txoj kev tsom xam
MOA muaj nyob rau thaum thov.
6. Kev ruaj ntseg thiab kev nyab xeeb
Kev ruaj ntseg:
Sealed and stored in a light-proof, dry, and cool environment (preferably 0-10℃ refrigeration), the shelf life is 2-3 years. At room temperature (25℃) with proper sealing, it can maintain stability for 12-18 months; high humidity (relative humidity >60%) accelerates degradation.
Kev nyab xeeb:
Tsawg toxicity. Qhov ncauj LD50 hauv nas yog ntau dua 5000 mg / kg. Tsis muaj cov tsos mob lom lom (piv txwv li, ntuav, lub cev puas tsuaj) tshwm sim nrog kev noj tshuaj ntau dhau los lossis ntau npaum li cas. Lub sij hawm ntev - supplementation (nyob rau hauv kev txwv txwv) tsis ua rau mob toxicity los yog cumulative puas rau daim siab thiab ob lub raum.
7.Cov txheej txheem tsim khoom
8. Cov neeg siv lus pom
9.Peb Daim Ntawv Pov Thawj
10.Peb cov neeg muas zaub
11. Exhibitions
Cim npe nrov: -lipoic acid 1077-28-7, Tuam Tshoj -lipoic acid 1077-28-7 manufacturers, lwm tus neeg, Hoobkas
