Cyanocobalamin 68-19-9

1. Taw qhia

Cyanocobalamin yog ib qho classic, dav siv daim ntawv ntawm vitamin B12. Pom tau nyob rau xyoo 1948, nws yog thawj qhov kev sib cais thiab cov txheej txheem teev cov vitamin B12 subtype, yog li feem ntau hu ncaj qha rau "vitamin B12" hauv kev siv ntau. Nws zoo nkaus li tsaus liab crystals los yog crystalline hmoov, me ntsis soluble nyob rau hauv dej thiab ethanol, nrog zoo heev stability rau lub teeb thiab kub.

Raws li ib tug prodrug, nws tsis muaj kev lom zem ua si ncaj qha- tom qab nkag mus rau hauv lub cev, nws yog metabolized nyob rau hauv lub siab mus rau active cov ntaub ntawv xws li methylcobalamin los pab txhawb nucleic acid synthesis, qe ntshav liab, thiab lub paj hlwb noj qab haus huv.

Tus nqi- zoo thiab ruaj khov, nws yog dav siv hauv cov chaw muag tshuaj, tshuaj kho mob, thiab cov khoom noj muaj zog los daws cov vitamin B12 tsis txaus.

2. Muaj nuj nqi

2.1.Kev ua haujlwm ntawm lub cev

Ua hauj lwm raws li ib tug prodrug, hloov mus rau hauv active vitamin B12 cov ntaub ntawv (xws li, methylcobalamin) nyob rau hauv lub siab los koom nyob rau hauv nucleic acid synthesis thiab cov ntshav liab.

Txhawb nqa lub paj hlwb kev noj qab haus huv los ntawm kev tswj hwm myelin sheath kev ncaj ncees thiab cov metabolism hauv neural.

Txhim khu kev nqus hlau thiab gastric acid secretion thaum ua ke nrog pantothenic acid, pab tsim hemoglobin.

2.2.Key Application Functions

Kho thiab tiv thaiv vitamin B12 tsis txaus-txoj kev mob (xws li, megaloblastic anemia, tshuaj-induced anemia).

Ua raws li cov khoom noj ntxiv los txhawb kev loj hlob ntawm cov nqaij qaib / tsiaj txhu, txhim kho kev siv cov protein ntau, thiab txhim kho cov ntses toxin.

Siv los ua zaub mov xim, khoom siv tshuaj pleev ib ce, deodorant tivthaiv, thiab ib puag ncig organohalide degrader.

3. Daim ntawv thov

3.1.Kev Kho Mob & Kev Kho Mob:Kho ntau yam vitamin B12 tsis txaus (piv txwv li, megaloblastic anemia, tshuaj -induced anemia). Ua ke nrog pantothenic acid, nws tiv thaiv pernicious anemia thiab txhim khu kev nqus hlau. Pab kho mob caj dab, neuralgia, kab mob siab, kev ua xua, thiab lwm yam. Txhim kho cov tsos mob neuropsychiatric xws li insomnia, nco tsis tau, thiab kev nyuaj siab. High kev nyab xeeb profile uas tsis muaj toxicity txawm nyob rau hauv cov koob tshuaj ntau heev.

3.2.Feed Kev Lag Luam:Siv los ua cov khoom noj ntxiv los txhawb kev loj hlob ntawm cov nqaij qaib thiab tsiaj txhu (tshwj xeeb yog cov tsiaj hluas) thiab txhim kho kev siv cov protein. Ua kom cov ntses ua siab ntev rau cov co toxins (xws li benzene, cov hlau hnyav) thiab txo cov neeg tuag. Ua haujlwm zoo rau kev hloov pauv "nqaij thiab pob txha noj mov" ncej-EU tus kab mob nyuj vwm, suav nrog ntau lub ntiaj teb vitamin B12 ntau lawm.

3.3.Lwm daim ntawv thov:Formulated rau hauv tshuaj pleev ib ce; ua cov xim rau cov khoom noj (piv txwv li, nqaij npua, ice cream); ua rau cov khoom deodorizing (xws li, activated carbon adsorbents, xab npum) kom tshem tawm cov ntxhiab tsw; siv nyob rau hauv kev tiv thaiv ib puag ncig kom degrade organohalides hauv av thiab dej saum npoo.

4.Quality Standard

5.Txoj kev tsom xam

MOA muaj nyob rau thaum thov.

6. Kev ruaj ntseg thiab kev nyab xeeb

Kev ruaj ntseg:

Thaum kaw thiab khaws cia rau hauv qhov chaw txias, qhuav (tsis txhob tshav ntuj ncaj qha thiab cov av noo), nws lub zog tuaj yeem khaws cia rau 2-3 xyoos. Qhov poob ntawm kev ziab thiab lwm yam khoom ua tau raws li tus qauv yuav tsum tau ua hauv lub txee lub neej.

Kev nyab xeeb:

Tsawg heev toxicity. Tsis muaj cov tshuaj lom neeg mob hnyav (piv txwv li, kev puas tsuaj ntawm lub cev, kev tuag) tshwm sim txawm tias nyob rau ntawm ultra- koob tshuaj ntau dhau ntawm qhov ncauj, tso rau hauv lub cev, lossis kev tswj hwm intramuscular. Ntev - kev noj tshuaj ntxiv tsis ua rau mob toxicity lossis kev puas tsuaj rau daim siab, ob lub raum, lossis lwm yam kabmob.

7.Cov txheej txheem tsim khoom

1.Raw Material Preparation: Cobalt Salt + 5,6-Dimethylbenzimidazole

2.Fermentation rau Synthesize Cobalamin Precursor

3.Extraction & Purification ntawm Precursor

4.Cyanation Reaction (Qhia Cyano Group)

5.Kem Chromatography Separation

6.Recrystallization Purification

7.Nqus kom qhuav (Moisture tsawg dua lossis sib npaug li 12.0%)

8.Quality Testing (Cov ntsiab lus / impurities / Heavy hlau)

9.Cov khoom tiav tiav (Purity ntau dua lossis sib npaug li 96.0%)

8. Cov neeg siv lus pom

9.Peb Daim Ntawv Pov Thawj

10.Peb cov neeg muas zaub

11. Exhibitions

Cim npe nrov: Cyanocobalamin 68-19-9, Tuam Tshoj cyanocobalamin 68-19-9 manufacturers, lwm tus neeg, Hoobkas