CAS 128446-35-5 Hydroxypropyl- -Cyclodextrin

1. Taw qhia

Hydroxypropyl- -cyclodextrin yog ib qho ntawm cov kev tshawb fawb tob tshaj plaws thiab siv dav siv cyclodextrin derivatives. Cov hmoov dawb, uas muaj qhov zoo solubility hauv dej, kuj tuaj yeem yaj hauv 50 feem pua ​​​​ethanol thiab methanol. Nws muaj qee yam txheeb ze hygroscopicity. Tab sis qhov txheeb ze ntawm qhov chaw ua haujlwm thiab kev ua haujlwm hemolytic yog qhov tsawg. Nws tsis muaj qhov khaus rau cov leeg thiab yog ib qho zoo tagnrho Solubilizer thiab excipient rau kev txhaj tshuaj. Kev sib koom tes ntawm B-cyclodextrin los yog nws cov derivatives nrog cov tshuaj los ua kom cov dej solubility ntawm cov tshuaj tau kawm ntau xyoo. Txawm li cas los xij, qhov qis solubility ntawm B-cyclodextrin txwv nws daim ntawv thov, thaum hydroxypropyl -8. Cyclodextrin muaj cov dej zoo solubility, siab thermal stability thiab tsis tshua muaj hemolysis, yog li nws yog ib qho tshuaj lom neeg tsawg, muaj kev nyab xeeb thiab siv tau zoo Solubilizer, thiab suav tias yog cov khoom siv rau kev txhaj tshuaj.

2. Muaj nuj nqi

Hauv tshuaj.
Hydroxypropyl- -cyclodextrin tuaj yeem daws cov teeb meem ntawm cov dej solubility ntawm cov tshuaj insoluble lossis insoluble (xws li cov nroj tsuag rho tawm).
Los ntawm molecular entrapment, peb tuaj yeem txhim kho cov tshuaj biosolubility, tswj cov tshuaj tso tawm tus nqi, txhim kho cov tshuaj bioavailability, txhim kho tshuaj stability thiab txo cov tshuaj phiv. Kev suav nrog cyclodextrin tuaj yeem ua rau muaj kev ruaj ntseg ntawm cov tshuaj rau lub teeb, txo qhov tsis muaj zog, ua kom ntev ntev, thiab txo qhov kev sib cuag toxicity rau tib neeg thiab tsiaj txhu, xws li pyrethroid, DDVP, organophosphorus thiab lwm yam kev suav nrog cov yam ntxwv saum toj no.
Hauv kev lag luam zaub mov.
Nws tuaj yeem txhim kho kev ruaj ntseg thiab lub sijhawm ntev ntawm cov khoom noj khoom haus molecules, npog lossis kho cov ntxhiab tsw phem thiab saj ntawm cov khoom noj khoom haus molecules, txhim kho cov txheej txheem tsim khoom thiab cov khoom zoo, thiab ua kom lub txee lub neej ntawm cov khoom. Kev lag luam khoom noj khoom haus siv cyclodextrin ua cov tshuaj tua kab mob rau cov txuj lom, pigments, preservatives, condiments, emulsifying foaming agents, thiab lwm yam.
Hauv tshuaj pleev ib ce.
Siv ua stabilizer, emulsifier thiab deodorant nyob rau hauv cov khoom siv tshuaj pleev ib ce, nws tuaj yeem txo cov stimulation ntawm cov organic molecules rau ntawm daim tawv nqaij thiab mucous daim nyias nyias hauv cov tshuaj pleev ib ce, txhim khu kev ruaj ntseg ntawm cov khoom zoo, tiv thaiv cov volatilization thiab oxidation ntawm cov as-ham, ua rau kom cov dej solubility ntawm insoluble. flavors thiab spices, thiab tswj qhov qeeb tso tawm thiab persistence ntawm fragrance. Cyclodextrin tuaj yeem siv los ua cov tshuaj tsw qab, lub suab hloov pauv, sab nraud matrix thiab deodorant hauv kev lag luam tshuaj txhua hnub.

3. Daim ntawv thov

Hydroxypropyl- -cyclodextrin feem ntau yog siv hauv cov khoom noj, tshuaj thiab tshuaj pleev ib ce.

4.Quality Standard

Tag nrho aerobic microbial suav

5.Txoj kev tsom xam

[kev txheeb xyuas] noj 5 feem pua ​​​​ntawm cov tshuaj aqueous 0.5ml, muab tso rau hauv 10ml xeem raj, ntxiv 2 tee ntawm ethanol tov ntawm 10 feem pua ​​-naphthol, co zoo, maj mam ntxiv 1ml sulfate raws phab ntsa. kuaj lub raj, thiab qhia lub nplhaib liab qab ntawm qhov sib txuas ntawm ob lub kua.
[kos] acidity thiab alkalinity ntawm cov khoom no yog 1.0g. Tom qab 40ml yog yaj nrog dej, nws raug txiav txim raws li txoj cai (txoj cai 0631). Tus nqi pH yuav tsum yog 5.0-7.5.
Qhov tseeb thiab xim ntawm cov tshuaj yog 2.5g, ntxiv dej 25ml kom yaj, xyuas raws li txoj cai (txoj cai dav dav 0901 thiab txoj cai dav dav 0902), cov tshuaj yuav tsum meej thiab tsis muaj xim.
Noj {{0}}.1 g ntawm chloride thiab xyuas raws li txoj cai (General Rule 0801). Piv nrog rau kev tswj cov tshuaj ua los ntawm cov txheej txheem sodium chloride tov 5.0ml, nws yuav tsum tsis txhob thicker (0.05 feem pua).
Beta cyclodextrin txog 1. noj Betacyclodextrin coj mus kuaj txog 50mg, precision hnyav, muab 100ml ntsuas lub raj mis, ntxiv dej kom yaj thiab dilute rau nplai, co zoo, raws li kev tswj kev daws. Raws li kev txiav txim siab ntawm kev ua haujlwm siab ua kua chromatography (txoj cai dav dav 0512), amino-bonded silica gel tau siv los ua cov muab tub lim, acetonitrile-dej (65:35) raws li lub sijhawm txawb, qhov sib txawv ntawm qhov ntsuas qhov ntsuas thiab sab kub ntawm 35 degree. 20 μl ntawm cov tshuaj tswj thiab 20 μl ntawm cov tshuaj ntsuam xyuas tau txhaj rau hauv cov kua chromatograph raws li, thiab cov chromatogram tau sau tseg. Yog tias muaj chromatographic ncov zoo ib yam nrog lub sijhawm khaws cia ntawm beta cyclodextrin ncov hauv cov qauv tshuaj chromatogram, lub ncov cheeb tsam yuav tsum raug xam raws li tus qauv txheej txheem sab nraud, thiab cov ntsiab lus ntawm beta cyclodextrin yuav tsum tsis pub tshaj 0.5 feem pua.
1Be 2-Propylene glycol txog 1g, qhov hnyav hnyav, muab tso rau hauv 10ml ntsuas lub raj mis, ntxiv methanol kom yaj thiab dilute mus rau qhov ntsuas, co zoo, raws li cov tshuaj ntsuam xyuas. Tsis tas li ntawd, 1 50mg 2-propanediol tau raug hnyav hnyav, muab tso rau hauv 100ml ntsuas lub raj mis, diluted nrog methanol rau qhov ntsuas, shaken zoo, thiab siv los ua cov tshuaj siv. Nws tau txiav txim siab raws li cov txheej txheem ntawm cov kuab tshuaj residual (General Rule 0861). Siv 100 feem pua ​​​​polydimethylsiloxane chemically crosslinked capillary kem li chromatographic kem, qhov pib kub yog 70 degree, cua sov mus txog 100 degree ntawm tus nqi ntawm 10 degree ib feeb, thiab ces nce mus rau 220 degree ntawm tus nqi ntawm 40 degree ib feeb rau 4 feeb. . Qhov kub ntawm qhov chaw txhaj tshuaj yog 250C; qhov ntsuas kub ntawm qhov ntsuas yog 280C; tus naj npawb ntawm cov ntawv theoretical xam los ntawm lub hauv paus ntawm 1m 2-propylene glycol ncov yuav tsum tsis pub tsawg tshaj 3000. Cov tshuaj siv thiab cov tshuaj ntsuam xyuas tau muab coj los txhaj rau hauv cov roj chromatograph raws li, thiab cov chromatogram tau sau tseg. Muab xam raws li thaj chaw ncov raws li tus qauv txheej txheem sab nraud, cov ntsiab lus ntawm 1 mine 2-propanediol yuav tsum tsis pub tshaj 0.5 feem pua.
Cov ntsiab lus noo noo ntawm cov khoom no yog txiav txim siab raws li kev txiav txim siab noo noo (Cov ntsiab lus dav dav 0832 txoj kev 1). Cov dej noo yuav tsum tsis pub tshaj 6.0 feem pua.
Cov hluav taws kub hnyiab yog 1. Qhov seem seem yuav tsum tsis pub tshaj 0.2 feem pua.
Cov hlau hnyav yog muab los ntawm cov khoom seem uas nyob hauv qab qhov hluav taws kub thiab tshuaj xyuas raws li txoj cai (Txoj cai 0821 thib ob). Cov ntsiab lus ntawm cov hlau hnyav yuav tsum tsis pub tshaj 10/1000000.
[Kev txiav txim siab cov ntsiab lus] txog 0.1 g ntawm hydroxypropoxyl tau txais los ntawm qhov hnyav thiab kev txiav txim siab ntawm methoxy, ethoxy thiab hydroxypropoxyl (Cov ntsiab lus dav dav 0712).

6.HPLC
 

7. Kev ruaj ntseg thiab kev nyab xeeb
Kev ruaj ntseg:
Nyob ruaj khov nyob rau hauv cov xwm txheej zoo (chav kub). Cov Ntaub Ntawv Kev ruaj ntseg muaj nyob rau ntawm koj qhov kev thov.
Kev nyab xeeb:
Raws li kev tshawb fawb, nws muaj kev nyab xeeb rau tib neeg noj.

8. Flow Chart
 

9. Cov neeg siv lus pom
Peb muaj cov khw muag khoom ntawm Alibaba, Chemicalbook thiab LookChem, los ntawm cov khoom lag luam zoo thiab cov kev pabcuam tsis tau txais kev pabcuam, peb tau txais ntau cov lus pom zoo.
 

10.Peb Daim Ntawv Pov Thawj
Tau ntau xyoo, peb tau cog lus rau cov khoom tsim khoom optimization thiab kev tsim kom zoo. Peb tau teeb tsa qhov kev tswj hwm zoo thiab tau txais daim ntawv pov thawj ntawm nws.

11.Peb cov neeg muas zaub
Peb tau tsim kev lag luam kev sib raug zoo nrog Abbott, Unilever, Shiseido, KANS thiab SIMM, thiab lwm yam.

12. Exhibitions
Peb feem ntau tuaj koom kev nthuav qhia thoob ntiaj teb, suav nrog CPhI, FIC, API, Vitafoods, SupplesideWest.

Cim npe nrov: cas 128446-35-5 hydroxypropyl- -cyclodextrin, manufacturers, lwm tus neeg, Hoobkas, lag luam wholesale, yuav, nqe, zoo tshaj plaws, tej, kev muag khoom