Sodium valproate hmoovyog ib qho tseem ceeb organic compound lug siv nyob rau hauv tshuaj synthesis, kho mob thiab ua zaub mov. Nws cov mis molecular yog C6H9O3Na, thiab nws tus lej CAS yog 137-40-6. Kab lus no yuav txheeb xyuas cov ntaub ntawv tseem ceeb no hauv cov ntsiab lus los ntawm kev taw qhia, txheej txheem tsim khoom, daim ntawv thov, kev ua haujlwm, thiab lwm yam ntawm sodium valproate.
1. Taw qhia txog Sodium Valproate
(1). Cov khoom siv tshuaj: Sodium valproate yog cov hmoov dawb lossis dawb dawb crystalline hmoov, uas muaj cov dej solubility zoo hauv dej thiab tsis yooj yim rau decompose nyob rau hauv ib puag ncig.
(2). Physical and chemical properties: The melting point of this compound is >300 degree, thiab lub ntiajteb txawj nqus yog 1.397. Nws tuaj yeem yog me ntsis soluble hauv cov kuab tshuaj organic, tab sis tsis tuaj yeem tshwm sim hauv nws lub xeev ntuj. Sodium valproate ruaj khov nyob rau hauv huab cua, tsis ntshai ntawm noo noo, tsis yooj yim rau decompose, thiab tsis-volatile.
(3) Kev siv ntau yam: Sodium valproate yog dav siv hauv tshuaj, tshuaj lom neeg kev lag luam, khoom noj khoom haus, khoom siv niaj hnub thiab lwm yam haujlwm. Kev tsim ntau yam tshuaj thiab cov cuab yeej kho mob yuav tsum tau sodium valproate ua raw khoom. Tsis tas li ntawd, nws tseem tuaj yeem siv ua zaub mov ntxiv, bactericide thiab preservative.
2. Kev siv tshuab ntawm sodium valproate
(1) Cov khoom siv: Ob yam khoom siv tshuaj - acrylic acid thiab acetone - yuav tsum tau npaj ua ntej tsim sodium valproate.
(2). Ethyl esterification cov tshuaj tiv thaiv: Ua ntej, ob qho khoom siv tshuaj sib xyaw ua ke, thiab lub ntim ntawm cov khoom noj yog tswj tau los tso cai rau cov sib tov kom tsis tu ncua tawm ntawm cov tshuaj tiv thaiv hluav taws xob, thiab tom qab ntawd cov khoom nkag mus rau nruab nrab ntawm cov tshuaj tiv thaiv ethyl esterification. Cov dej sib cais los ntawm cov cuab yeej kho dej ntws ncaj qha mus rau hauv cov kav dej qis.
(3).Crystalization: Tom qab cov tshuaj tiv thaiv ethyl esterification tiav, crystallization yuav tsum tau. Cov tshuaj tiv thaiv yuav tsum tau pretreated los yog ib tug chemical agent yog ntxiv rau precipitate sodium valproate los ntawm cov tshuaj tiv thaiv.
(4). Kev ziab: Tom qab txo qis, txias thiab nqus, ziab yuav tsum tau tso cai rau sodium valproate kom pom qee yam ntawm lub cev.
(5). Kev Tswjhwm Zoo: Hauv cov txheej txheem tsim khoom ntawm sodium valproate, ntau yam tsis zoo hauv kev tsim khoom kuj yuav tsum tau tswj xyuas kom ruaj khov zoo. Sodium valproate feem ntau yog hais txog GMP cov lus pom zoo hauv Tebchaws Meskas thiab Europe.
3. Daim ntawv thov ntawm sodium valproate
(1). Cov khoom lag luam tshuaj: Sodium valproate yog ib qho tseem ceeb raw cov ntaub ntawv rau ntau yam tshuaj, xws li tshuaj kho kev puas siab puas ntsws, sedatives, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv rog, tshuaj tua kab mob thiab tshuaj steroids.
(2) Khoom noj khoom haus ntxiv: Sodium valproate yog siv dav hauv kev ua zaub mov, thiab siv los ntxiv ua npuas ncauj thiab tuav cov proteins.
(3) Preservative: Ntxiv nrog rau ob daim ntawv thov saum toj no, sodium valproate kuj yog ib qho tshuaj tiv thaiv zoo thiab yog siv dav hauv casein, napkins, thiab lwm yam.
4. Kev ua haujlwm ntawm sodium valproate
(1). Tswj pH tus nqi: Sodium valproate tuaj yeem siv los kho pH tus nqi ntawm cov zaub mov thiab tshuaj pleev ib ce. Qhov sib ntxiv ntawm sodium valproate hauv kev ua zaub mov tuaj yeem tswj hwm pH ntawm cov zaub mov, yog li ua kom nws lub sijhawm khaws cia zoo heev.
(2) Ua kom lub neej cia: Sodium valproate tuaj yeem siv los ua cov khoom noj khoom haus, tshuaj, thiab tshuaj kom ntev lawv lub neej kev pab cuam los ntawm inhibiting kev loj hlob thiab kev loj hlob ntawm cov kab mob.
(3). Anti-inflammatory thiab sedative: Sodium valproate kuj tseem siv tau los ua cov tshuaj sedative thiab anti-inflammatory teebmeem, thiab tuaj yeem siv los kho ntau yam mob hauv lub cev thiab mob thiab lwm yam kab mob.
Hauv cov ntsiab lus, sodium valproate, uas yog ib qho tseem ceeb ntawm cov organic compounds, muaj cov ntawv thov dav dav hauv kev lag luam tshuaj, zaub mov thiab tshuaj lom neeg kev lag luam. Raws li ib qho tseem ceeb ntawm cov khoom siv raw khoom thiab cov khoom siv ntxiv, kev siv sodium valproate tuaj yeem pab cov tuam txhab tsim tshuaj thiab cov khoom noj muaj txiaj ntsig zoo, kev nyab xeeb thiab kev ntseeg siab, thiab ua tau raws li cov neeg xav tau kev noj qab haus huv thiab lub neej zoo.
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