PQQ Disodium ntsev hmoov 122628-50-6

PQQ Disodium ntsev hmoov 122628-50-6

1. Taw qhia

PQQ Disodium Salt Powder 122628-50-6 yog ib hom henna hmoov.It yog sodium ntsev derivative ntawm pyrroloquinoline quinone (PQQ-2Na). Nws yog lub active ingredient ntawm tam sim no coj mus muag khoom noj qab haus huv. Nws muaj cov paj hlwb loj hlob uas ua rau muaj kev ua si thiab tiv taus Parkinson tus kab mob. Nws muaj qee yam cuam tshuam thiab tuaj yeem tiv thaiv lub siab tiv thaiv kab mob.

2. Specification

3. Flow daim ntawv qhia

4. Test Report

5. Kev xeem

5.1. Qhov tshwm sim

Reddish Brown Powder.

5.2. UV absorbance:

Siv cov qauv 28mg rau 100ml ntim ntim, ntxiv dej ntshiab ultrasonic dissolving, thiab diluted rau

scale, co, ntsuas 5.0 ml rau 100 ml volumetric hwj.

Kev npaj cov cuab yeej -ultraviolet-pom spectrophotomete, kuaj hauv 233nm, 259nm thiab

322nm, nqus tus nqi: A233, A259, A322, Cov txiaj ntsig raws li hauv qab no:

A233/A259=0.90±0.09

A322/A259=0.56±0.03

5.3. Poob rau ziab

Tsis ntau tshaj 12.0% (1 g, 105 ℃, 3 teev).

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5.4. Arsenic

Tsis ntau tshaj 2PPM

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5.5. Hnyav Hlau

Tsis ntau tshaj 10PPM

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5.6. HPLC Purity thiab kev soj ntsuam ntawm PQQ

5.6.1 Chromatographic mob

a) Khoom siv: HPLC

b) Kem: C18, YMC - Pob A - 302 ODS; 5m ;ua. 4.6 hli * 150 hli los yog sib npaug

c) Mobile theem:

Muaj pes tsawg leeg: 0.1M acetic acid-0.1M ammonium acetate=(30:70) (PH5.1);

Txoj kev npaj:

A: acetic acid 1.8g rau hauv 300ml dej ntshiab,

B: ammonium acetate 5.4g rau hauv dej ntshiab, Ntxiv dej ntshiab rau 700ml;

Sib tov A thiab B, siv acetic acid hloov PH rau 5.1.

Ntes: 259nm (wavelength)

Kub: 40 ℃

Tus nqi ntws: 1.5mL / min

Txhaj ntim: 20uL

Lub sijhawm ua haujlwm: 30 min

5.6.2 Cov qauv kev daws teeb meem

Ua kom raug hnyav 23mg rau 50ml ntim ntim, siv lub sijhawm txawb, thiab coj mus rau ntim,

co zoo

5.6.3 Txuj kev daws teeb meem

Ua kom raug hnyav 20mg PQQ rau 50ml ntim ntim, siv lub sijhawm txawb yaj, coj mus rau ntim,

thiab co zoo

5.6.4 Analytical ib ntus

a) Ua thaum xub thawj 5 txhaj tshuaj ntawm cov qauv kev daws teeb meem thiab suav cov txheeb ze tus qauv sib txawv

(RSD %) ntawm PQQ peaks uas yuav tsum tsis pub tshaj 2.0%.

b) Siv cov kua dej tsis txaus (theem mobile), cov qauv kev daws teeb meem, sau chromatogram.

c) Txhaj tshuaj tus qauv thiab xam qhov txheeb ze tus qauv sib txawv (RSD %) ntawm PQQ peaks (6)

uas yuav tsum tsis txhob ntau tshaj 2.0%.

Kev suav cov mis:

HPLC purity (%)=(APQQ / Tag nrho cov ncov)

Nco tseg:

APQQ: thaj tsam ntawm cov qauv kev daws teeb meem

Tag nrho lub ncov: tag nrho cheeb tsam

Kev ntsuam xyuas ntawm PQQ:

ASSAY of PQQ(%)=(AX/AS)(CR/CX)×100%

Nco tseg:

CR yog qhov concentration (mg / ml) ntawm PQQ hauv cov qauv tshuaj;

CX yog qhov concentration (mg / ml) ntawm PQQ hauv cov qauv kev daws teeb meem;

AX yog thaj tsam ntawm lub ncov ntawm PQQ hauv cov qauv kev daws teeb meem;

AS yog thaj tsam ntawm lub ncov ntawm PQQ hauv kev daws teeb meem

5.7. Sodium / PQQ ratio

5.7.1Residue ntawm Ignition

Kub: 750 ℃ ​​Sijhawm: 60 feeb

Siv 2015 Suav Pharmacopoeia (plaub ntu)

A=Residue ntawm ignition (%) =

((ignition+ qhov hnyav ntawm qhov tsis muaj crucible) - qhov hnyav ntawm qhov tsis muaj crucible) / qhov hnyav ntawm cov qauv

5.7.2 Kev ntsuas ntawm sodium

Kev ntsuas Sodium (%)=A x 46 / 142

5.7.3 Sodium/PQQ ratio=Assay of sodium (%) x330 / Assay of PQQ (%) x23

5.8. Microbiology txwv

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5.9. Residual kuab tshuaj (Ethanol)

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6. Muaj nuj nqi

1. PQQ Disodium Salt Powder 122628-50-6 tuaj yeem txhim kho tib neeg kev tiv thaiv kab mob;

2. Nws tuaj yeem txo cov dawb radical puas rau tib neeg lub cev;

3. Nws tuaj yeem tiv thaiv daim siab puas tsuaj, tswj ntau yam kab mob paj hlwb;

4. Nws tuaj yeem tiv thaiv thiab kho Alzheimer' tus kab mob, tiv thaiv qog noj ntshav;

5. Nws tuaj yeem txhawb nqa cov synthesis ntawm kev loj hlob yam.

   
   

7. Daim ntawv thov

QQ Disodium Salt Powder 122628-50-6 tuaj yeem siv rau hauv kev kho mob cov khoom lag luam los ua tshuaj ntxiv.

8. Kev ruaj ntseg thiab kev nyab xeeb
Kev ruaj ntseg:
Nyob ruaj khov nyob rau hauv cov xwm txheej zoo (chav kub). Cov Ntaub Ntawv Kev ruaj ntseg muaj nyob rau ntawm koj qhov kev thov.
Kev nyab xeeb:
Raws li GARS (Feem ntau Pom Zoo Raws Li Kev Nyab Xeeb) Daim Ntawv Ceeb Toom ntawm Teb Chaws Asmeskas, nws muaj kev nyab xeeb rau tib neeg noj.

9. Daim ntawv pov thawj

Tau ntau xyoo, peb tau cog lus rau cov khoom tsim khoom optimization thiab kev tsim kom zoo. Peb' tau teeb tsa kev tswj hwm zoo thiab tau txais daim ntawv pov thawj ntawm nws.

10. Exhibition

Peb feem ntau tuaj koom kev nthuav qhia thoob ntiaj teb, suav nrog CPhI, FIC, API, Vitafoods, SupplesideWest.

11. Peb Cov Neeg Siv Khoom

Peb' tau tsim kev lag luam kev sib raug zoo nrog Abbott, Unilever, Shiseido, KANS thiab SIMM, thiab lwm yam.

12. Cov neeg muas zaub'Review

13. FAQ

Q1: Koj puas muaj MOA ntawmPQQ Disodium ntsev hmoov 122628-50-6?

Re: Yog, peb muab tag nrho MOA rau kev txiav txim.

Q2: yog koj liPQQ Disodium ntsev hmoov 122628-50-6 femented los yog synthesized?

Re: Nws yog fermented.

Q3: Dab tsi yog qhov siab tshaj plaws purity koj tuaj yeem tsim tau?

Re: HPLC 99%.

Q4: Koj puas tuaj yeem xa nws nrog lub npe tiag?

Re: Tseeb, kev xa khoom lub npe tiag yog qhov tseem ceeb rau cov neeg siv khoom.

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