Achyranthes Bidentata Polysaccharide

1. Taw qhia
Achyranthes Bidentata Polysaccharide (ABP) yog ib qho tshuaj lom neeg muaj zog polysaccharide muab rho tawm los ntawm cov hauv paus ntawm cov tshuaj suav tshuaj Achyranthes bidentata. Nws yog dav pom nyob rau hauv cov tsiaj, nroj tsuag thiab microbial cov ntaub so ntswg, muaj ntau yam pharmacological teebmeem, thiab muaj qhov zoo ntawm kev nyab xeeb, ruaj khov kev txiav txim, me me kev phiv, dav daim ntawv thov, me me kev puas tsuaj rau lub cev, thiab tuaj yeem txhaj thiab noj qhov ncauj. .

2. Lub luag haujlwm tseem ceeb
2.1. Hnub nyoog ncua sij hawm thiab cov teebmeem antioxidant
ABP tuaj yeem tswj hwm kev loj hlob ntawm tes, kev sib txawv thiab apoptosis, thiab rau qee qhov kev tswj hwm lub ntuj thiab qhov muaj feem cuam tshuam cov pa oxygen hauv lub cev. Hauv cov qauv nas laus, ABP tuaj yeem ua rau qeeb lossis tseem thaiv cov oxidation ntau dhau ntawm lub hlwb thiab daim siab cov ntaub so ntswg, yog li ua tiav cov txiaj ntsig ntawm kev ncua kev laus. Ib pab pawg tshawb fawb tau kawm txog cov khoom thiab kev tiv thaiv kev laus ntawm ABP thiab pom tias cov khoom loj-molecule ntawm ABP tsis muaj kev tiv thaiv kev laus ntawm Drosophila, thaum lub me me-molecule tivthaiv ntawm ABP nyob rau hauv ntau theem ua rau qhov nruab nrab lub cev loj ntawm lub cev. Drosophila los ntawm 3.85 feem pua ​​​​rau 5.47 feem pua ​​​​thiab ncua lub neej nruab nrab ntawm Drosophila 2.61 feem pua ​​​​rau 3.16 feem pua. Lawv kuj pom tias ABP nce qhov ciaj sia taus ntawm H2O2- kho 2BS hlwb, txo qhov zoo ntawm SA- - gal staining thiab inhibited qib ntawm malondialdehyde (MDA) thiab monoamine oxidase-B (MAO- B), thiab nce kev ua haujlwm ntawm superoxide dismutase (SOD), yog li ua tiav cov nyhuv anti-senescence.

2.2. Kev tiv thaiv qog nqaij hlav thiab kev tiv thaiv kev tiv thaiv kab mob
Kev ua haujlwm lom neeg ntawm kev hloov kho ABP tau txhim kho zoo heev, thiab nws tuaj yeem cuam tshuam kev loj hlob thiab kev sib txawv ntawm cov qog hlwb hauv vivo los ntawm kev nce cov leukocytes hauv lub cev cov ntshav. Ntau qhov kev tshawb fawb tau pom tias qhov hloov kho ABP muaj qhov cuam tshuam loj ntawm cov qog nqaij hlav thiab tuaj yeem ua rau NK kev ua si.

2.3. Anti-inflammatory teebmeem
ABP muaj cov tshuaj tua kab mob vim muaj cov tshuaj steroids, saponins, alkaloids thiab lwm yam khoom. Nws tau pom tias inhibition ntawm cell adhesion los ntawm E. coli feem ntau tshwm sim ntawm qhov concentration ntawm 0.8 mg/mL, qhia tias ABP muaj qhov muaj zog inhibitory nyhuv ntawm E. coli ntawm qhov concentration no. Ib qho kev sim tau kawm txog cov txiaj ntsig ntawm ABP ntawm cov kab mob hauv plab hnyuv ntawm piglets nrog 160 weaned piglets thaum muaj hnub nyoog 28 hnub, thiab pom tias pawg ABP tau zoo dua li cov tshuaj tua kab mob hauv inhibiting plab hnyuv E. coli thiab txhawb cov kab mob plab hnyuv, thiab cov nyhuv no. tau hais txog tus nqi ntawm ABP ntxiv. Tsis tas li ntawd, ABP muaj qhov txo qis ntawm kev mob ntsws asthma ntev. Ib txoj kev tshawb fawb ntawm cov txheej txheem ntawm Th1 / Th2 tshuav nyiaj li cas hauv kev mob ntsws asthma tau pom tias ABP txo qis txoj hlab pa hauv cov nas mob hawb pob, txo qis kev tsim cov hlwb xws li mob eosinophils (EOS), thiab txo qhov sib ntxiv ntawm dexamethasone hauv kev kho mob. mob hawb pob.

2.4. Txhawb cov ntshav ncig thiab ua kom cov ntshav ncig
ABP muaj cov nyhuv activating ntshav thiab tshem tawm cov av, tonifying lub siab thiab lub raum, thiab inducing cov ntshav mus downward. Qee cov kws tshawb fawb tau kawm txog cov nyhuv anticoagulant ntawm ABP thiab pom tias ABP tuaj yeem ua kom ntev lub sijhawm coagulation hauv nas, plasma prothrombin lub sij hawm hauv nas, thiab ib nrab lub sij hawm thromboplastin hauv cov av nplaum dawb, uas muaj cov nyhuv coagulant, thiab nws ntseeg tau tias qhov ua tau zoo ntawm Bupleurum hauv. Kev ua kom cov ntshav ncig tuaj yeem cuam tshuam nrog cov nyhuv anticoagulant ntawm ABP.

2.5. Txo cov ntshav qabzib
ABP tuaj yeem txo qis cov ntshav qabzib hauv cov nas uas tshwm sim los ntawm tetraoxonine thiab epinephrine, thiab txhawb kev sib txuas ntawm daim siab glycogen hauv cov nas mob ntshav qab zib.

2.6. Anticoagulant nyhuv
Achyranthes Bidentata Polysaccharide muaj cov nyhuv ua kom ntshav. Kev sim tshawb fawb txog cov nyhuv anticoagulant ntawm B. bovis polysaccharide pom tias B. bovis polysaccharide tuaj yeem ua kom ntev lub sij hawm coagulation hauv nas, plasma prothrombin lub sij hawm hauv nas, thiab ib nrab lub sij hawm thromboplastin hauv av nplaum dawb, thiab muaj cov nyhuv coagulant, thiab ntseeg tau tias. Kev ua tau zoo ntawm B. bovis hauv kev ua kom cov ntshav tuaj yeem cuam tshuam nrog cov nyhuv anticoagulant ntawm B. bovis polysaccharide.

3. Cov ntawv thov
Achyranthes Bidentata Polysaccharide tuaj yeem siv los tiv thaiv thiab kho qee yam kab mob xws li qog nqaij hlav; nyob rau hauv cov tsiaj ua liaj ua teb ntau lawm, nws yuav siv tau raws li ib tug ntsuab thiab environmentally phooj ywg pub additive.

4. Flow Chart
Raw khoom → kev lag luam ethanol reflux → ethanol kua → ntau rho tawm → nag lossis daus → ntxuav → ziab → khoom crude → refining → Achyranthes bidentata polysaccharide

5. Tus Qauv Zoo

Raws li Enterprise Standard

6. Txoj kev tsom xam

MOA muaj nyob rau thaum thov.

7. Siv Spetrum

8. Kev ruaj ntseg thiab kev nyab xeeb

Kev ruaj ntseg:

Nyob ruaj khov nyob rau hauv cov xwm txheej zoo (chav kub). Cov Ntaub Ntawv Kev ruaj ntseg muaj nyob rau ntawm koj qhov kev thov.
Kev nyab xeeb:

Raws li GARS (Feem ntau Pom Zoo Raws Li Kev Nyab Xeeb) Daim Ntawv Ceeb Toom ntawm Teb Chaws Asmeskas, nws muaj kev nyab xeeb rau tib neeg siv.

9. Cov neeg siv lus pom

10. Peb Daim Ntawv Pov Thawj

11. Peb Cov Neeg Siv Khoom

12. Exhibition

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