Spermidine 124-20-9

1. Taw qhia

Spermidine yog ib qho hnyav molecular aliphatic carbide uas muaj peb pawg amino. Nws yog ib qho ntawm ntuj polyamines uas muaj nyob rau hauv tag nrho cov kab mob. Raws li ib qho tseem ceeb raw khoom rau kev siv tshuaj synthesis, nws yog dav siv nyob rau hauv synthesis ntawm kws tshuaj intermediates. Nws koom nrog ntau cov txheej txheem lom neeg hauv cov kab mob, xws li tswj cov cell proliferation, cell aging, organ development, immunity, cancer and other physiological and pathological processes. Cov kev tshawb fawb tsis ntev los no tau pom tias nws ua lub luag haujlwm tseem ceeb hauv kev tswj hwm ntawm synaptic plasticity, oxidative stress thiab autophagy nyob rau hauv lub paj hlwb.

2. Flow Chart

3.Quality Standard

4.Chromatogram

5. Muaj nuj nqi

Spermidine muaj cov haujlwm hauv qab no:

1) Pib ua cell phagocytosis

Spermidine tuaj yeem tiv thaiv lub hnub nyoog ntsig txog kev nco poob, qhov tshwm sim ntawm kev sib koom tes los ntawm cov kws tshawb fawb German thiab Austrian. Thaum lub Cuaj Hlis 1, 2013, cov txiaj ntsig tau tshaj tawm hauv online tsab ntawm Nature Neuroscience. Cov txiaj ntsig ntawm pab pawg kawm los ntawm xibfwb Stephen Siegrest ntawm Free University of Berlin hauv tebchaws Yelemes thiab xibfwb Frank Madeo ntawm University of Karl Franzen hauv Austria qhia tias spermidine tuaj yeem kho lub hlwb kev ua haujlwm ntawm cov txiv hmab txiv ntoo laus mus rau theem ntawm lawv cov hluas. Hauv biology, cov txheej txheem nco ntawm yoov thiab nas zoo ib yam li cov tib neeg ntawm qib molecular. Yog li ntawd, cov kws tshawb fawb ntseeg tias txoj kev tshawb no yuav pab tsim cov tshuaj kom ncua qhov pib ntawm Alzheimer's disease.

Biologists tau ua pov thawj tias cov tshuaj endogenous spermidine tuaj yeem ua rau autophagy hauv hlwb. Thaum Lub Kaum Hli 2009, Xib Fwb Madeo tau luam tawm ib tsab ntawv hais txog "Spermidine induced autophagy txhawb nqa lub neej ntev" hauv Nature Cell Biology. Kev tshawb fawb ntxiv los ntawm pab pawg tshawb fawb sib koom tau pom tias los ntawm kev pub spermidine rau cov txiv hmab txiv ntoo yoov, cov protein ntau hauv lawv lub hlwb tau txo qis, ua rau muaj kev nce hauv lawv lub peev xwm nco. Cov txiaj ntsig no tau txheeb xyuas los ntawm kev ntsuas, vim tias cov txiv hmab txiv ntoo yoov nco ntsoov qhov lawv tau kawm los ntawm kev kawm txog kev hloov pauv hauv Pavlovian, thiab kho lawv tus cwj pwm yav tom ntej kom haum.

Cov kws tshawb fawb hais tias kev thov kev tshawb fawb rau cov neeg mob yog lub hom phiaj tom ntej ntawm pab pawg tshawb fawb sib koom ua ke. Tib neeg lub cim xeeb pib poob qis tom qab hnub nyoog 50. Thaum koj muaj hnub nyoog, qhov kev lwj no nrawm dua. Vim qhov nce hauv lub neej expectancy, muaj qhov nce ntxiv hauv cov hnub nyoog ntsig txog dementia. Qhov concentration ntawm spermidine hauv Drosophila thiab tib neeg kuj txo qis nrog hnub nyoog. "Yog hais tias spermidine supplementation tuaj yeem ncua qhov pib ntawm dementia, nws sawv cev rau qhov tseem ceeb rau cov neeg mob thiab tib neeg."

2) ncua kev laus ntawm cov protein

Cov nyhuv ntawm spermidine ntawm cov protein sib txawv molecular hnyav sib txawv hauv qhov loj, thiab qee qhov hnyav molecular hnyav hnyav nce ntxiv nrog rau lub sijhawm kho spermidine ntev, qhia tias tej zaum yuav muaj protein ntau synthesis, tab sis qhov no ntawm cov protein suav rau ib feem me me ntawm cov spermidine. tag nrho cov ntsiab lus ntawm cov protein, thiab cov nyhuv ntawm qhov nruab nrab thiab me me molecular yuag proteins tsis tseem ceeb. Cov proteins tseem ceeb tseem tsis tau hloov pauv thaum 72 teev ntawm kev kho mob, Los ntawm cov txiaj ntsig no, nws tuaj yeem suav tau tias lub luag haujlwm ntawm cov protein sib txawv hauv cov txheej txheem kev laus yuav txawv, thiab qee qhov loj molecular yuag proteins tuaj yeem ua lub luag haujlwm tseem ceeb hauv kev tswj lub cev. aging txheej txheem ntawm nplooj. Thaum cov proteins no pib degrade, kev laus yog qhov yuav tsum tau zam, thiab tswj kev degradation ntawm cov proteins no tuaj yeem ncua cov txheej txheem kev laus, Yog vim li cas spermidine tuaj yeem ncua nws txoj kev laus tuaj yeem dag hauv kev txhawb nqa cov synthesis ntawm cov proteins lossis tiv thaiv lawv cov degradation.

6. Daim ntawv thov

1) Cov khoom no yog siv rau hauv kev tshawb fawb tshuaj thiab wrinkles whitening hauv tshuaj pleev ib ce.

2) Inhibition ntawm neuronal NO synthase (nNOS). Kev khi thiab nag lossis daus ntawm DNA; kuj tseem siv los ntxuav DNA-binding protein. Stimulation ntawm T4 polynucleotide kinase kev ua haujlwm.

Cov khoom no yog siv rau hauv kev tshawb fawb tshuaj thiab wrinkles whitening hauv tshuaj pleev ib ce.

7. Kev Tshawb Fawb Txog Kev Nyab Xeeb thiab Kev Nyab Xeeb

Peb tau ua ntau yam kev ruaj ntseg thiab kev nyab xeeb kawm txog cov khoom no, raws li cov ntaub ntawv ceev ceev thiab kev ruaj ntseg mus sij hawm ntev, nws qhia cov yam ntxwv ruaj khov; raws li kev tshawb nrhiav tsiaj txhu, nws qhia tau tias muaj kev nyab xeeb.

8. Daim ntawv pov thawj

KONO CHEM CO.LTD tau lees paub los ntawm ISO9001: 2015 los ntawm lub cev muaj ntawv pov thawj

9. Cov neeg siv khoom loj

KONO CHEM CO.LTD tau dhau los ua tus tswv cuab tseem ceeb hauv kev muab Spermidine rau lub ntiaj teb nto moo zaub mov, tshuaj thiab tshuaj pleev ib ce

10. Exhibitions

Peb ib txwm tuaj koom kev ncaj ncees xws li CPHi, FIC, Vitafoods, Supplyside sab hnub poob thiab nthuav peb lub lag luam nyob rau hauv cov ces kaum ntawm lub ntiaj teb no, thiab xav kom cov neeg nyob rau hauv lub ntiaj teb no tau txais txiaj ntsim los ntawm Kono Chem Co., ltd.

11.Cov neeg siv lus pom

Cim npe nrov: spermidine 124-20-9, manufacturers, lwm tus neeg, Hoobkas, lag luam wholesale, yuav, nqe, zoo tshaj plaws, tej, kev muag khoom