Pepsin 9001-75-6

1. Taw qhia

Pepsin yog ib qho enzyme uas tuaj yeem txhawb kev zom cov protein hauv cov zaub mov. Nws qhov chaw yog pepsinogen, uas yog secreted los ntawm lub ntsiab hlwb nyob rau hauv lub plab. Raws li kev ua ntawm gastric acid, pepsinogen tuaj yeem tsim pepsin thiab ua tiav lub hom phiaj ntawm kev zom cov protein hauv cov zaub mov. Rau cov neeg mob gastritis thiab gastric ulcer, tsis muaj pepsin nyob rau hauv lub cev. Qhov laj thawj tseem ceeb yog tias cov ntsiab lus ntawm gastric acid tsawg dhau los hloov pepsinogen rau hauv pepsin, uas cuam tshuam rau kev zom zaub mov thiab nqus cov protein, ua rau mob plab, tsam plab, acid regurgitation, belching thiab lwm yam tsos mob.

Kev txiav txim siab ntawm pepsin tuaj yeem siv los txheeb xyuas neurogenic hypoacidosis. Thaum muaj me ntsis los yog tsis muaj pepsin, cov ntsiab lus ntawm pepsin nyob rau hauv lub qub yog qee zaum ib txwm, thaum tom kawg yog tsis muaj hydrochloric acid thiab pepsin tib lub sijhawm. Nws yog feem ntau ntseeg tias gastric hypoacidosis yog tshwm sim los ntawm cov organic hloov pauv hauv plab hnyuv, tshwj xeeb tshaj yog rau cov ntshav tsis txaus, acidosis, thiab pepsin secretion. Kev tso tawm ntawm pepsin nyob rau hauv cov neeg mob uas mob gastritis, mob plab hnyuv dilatation thiab mob duodenitis feem ntau txo. Feem ntau, cov kev ua ntawm pepsin yog nce nyob rau hauv cov neeg mob siab gastric acid secretion. Xyoo 1836, (Theodor Schwann) nrhiav tau ib hom enzyme uas tuaj yeem koom nrog hauv kev zom zaub mov hauv kev tshawb fawb txog kev zom zaub mov, thiab hu ua pepsin. Pepsin kuj yog thawj enzyme tau los ntawm cov tsiaj.

Tsuas yog proteolytic enzyme nyob rau hauv lub plab. Qhov zoo tshaj pH tus nqi yog 1.5 ~ 2.0. Lub ntsiab tseem ceeb ntawm kev ua ntawm pepsin yog peptide daim ntawv cog lus uas muaj ntxhiab los yog acidic amino acids. Cov enzyme no yog tsim los ntawm cov hlwb tseem ceeb ntawm cov qog nqaij hlav hauv plab thiab tso tawm hauv daim ntawv zymogen granules. Tom qab ua haujlwm los ntawm hydrochloric acid hauv cov kua txiv hmab txiv ntoo, nws muaj peev xwm zom cov protein. Cov tshuaj pepsin tuaj yeem muab rho tawm los ntawm lub plab ntawm npua, nyuj thiab yaj thiab siv rau kev zom zaub mov.

2.Main Function

Pepsin yog zais los ntawm cov hlwb tseem ceeb ntawm lub plab hnyuv, thiab ua rau pepsin nyob rau hauv cov xwm txheej ntawm pH1.5 ~ 5.0. Nws decomposes cov protein rau hauv peptides, thiab ib feem ntawm nws yog decomposed rau hauv tyrosine, phenylalanine thiab lwm yam amino acids. Kev txiav txim siab ntawm pepsin hauv cov kua txiv plab tuaj yeem siv los paub qhov txawv ntawm neurogenic hypoacidosis thiab gastric hypoacidosis. Thaum lub plab acid tsawg dhau los yog tsis txaus, cov ntsiab lus ntawm pepsin nyob rau hauv lub qub yog qee zaum ib txwm, thaum tom kawg yog tsis muaj hydrochloric acid thiab pepsin tib lub sijhawm. Nws yog feem ntau ntseeg tias gastric hypoacidosis yog tshwm sim los ntawm cov organic hloov pauv hauv plab hnyuv, tshwj xeeb tshaj yog rau cov ntshav tsis txaus, acidosis, thiab pepsin secretion. Kev tso tawm ntawm pepsin nyob rau hauv cov neeg mob uas mob gastritis, mob plab hnyuv dilatation thiab mob duodenitis feem ntau txo.

3. Daim ntawv thov

Feem ntau, kev ua ntawm pepsin nce rau cov neeg mob uas muaj cov kua qaub ntau hauv plab, xws li duodenal rwj. Xyoo 1836, Theodor Schwann nrhiav tau ib yam khoom uas tuaj yeem koom nrog hauv kev zom zaub mov thaum nws tshawb fawb txog kev zom zaub mov, thiab hu ua pepsin. Pepsin kuj yog thawj enzyme tau los ntawm cov tsiaj. Tsuas yog proteolytic enzyme nyob rau hauv lub plab. Qhov zoo tshaj pH tus nqi yog 1-2. Lub ntsiab tseem ceeb ntawm kev ua ntawm pepsin yog peptide daim ntawv cog lus uas muaj ntxhiab los yog acidic amino acids. Cov enzyme no yog tsim los ntawm cov hlwb tseem ceeb ntawm cov qog nqaij hlav hauv plab thiab tso tawm hauv daim ntawv zymogen granules. Tom qab ua haujlwm los ntawm hydrochloric acid hauv cov kua txiv hmab txiv ntoo, nws muaj peev xwm zom cov protein. Tshuaj pepsin tuaj yeem muab rho tawm los ntawm npua plab thiab siv rau kev zom zaub mov. Cov tshuaj no yog txwv tsis pub rau peptic ulcer.

4.Quality Standard

5.Txoj kev tsom xam

1. Siv rau 6 lub raj kuaj, peb ntawm cov uas raug ntxiv nrog 1ml ntawm cov kev siv tshuaj, thiab lwm yam peb yog precisely ntxiv nrog 1ml ntawm cov tshuaj ntsuam xyuas. Muab lawv tso rau hauv 37 degree ± 0.5 degree dej da dej, kom lawv sov li 5 feeb, thiab meej ntxiv 5ml ntawm cov tshuaj ntsuam xyuas hemoglobin preheated rau 37 degree ± 0.5 degree, co nws nce, thiab raug lub sijhawm, thiab hnov ​​​​mob rau 10 feeb hauv 37 degree ± 0.5 degree dej da dej.

2. Ntxiv 5ml ntawm 5 feem pua ​​trichloroacetic acid tov kom raug tam sim ntawd, co nws kom zoo, lim nws, thiab coj cov filtrate tas li rau standby. Noj lwm ob lub raj, ntxiv 5ml ntawm cov tshuaj hemoglobin rau txhua lub raj, cia nws ntub rau 10 feeb hauv dej da dej ntawm 37 degree ± 0.5 degree, thiab tom qab ntawd ntxiv 5ml ntawm 5 feem pua ​​trichloroacetic acid tov, ib qho ntxiv 1ml ntawm cov tshuaj ntsuam xyuas, lwm qhov ntxiv 1ml ntawm cov tshuaj hydrochloric acid saum toj no, co nws, lim nws, thiab coj cov filtrate tas li raws li kev tswj tsis pub dhau ntawm cov qauv kuaj thiab cov qauv tswj, ntsuas qhov nqus ntawm lub wavelength ntawm 275 nm raws li spectrophotometric (Appendix IVA), thiab xam qhov nruab nrab tus nqi AS thiab A, xam raws li cov qauv hauv qab no. A × Ws × N Protease kev ua si ib 1g (unit)=As × W × kaum × 181.19 Qhov twg AS yog qhov nruab nrab absorbance ntawm cov khoom siv; A yog qhov nruab nrab absorbance ntawm cov qauv kuaj; Ws yog tus nqi ntawm tyrosine hauv txhua 1ml ntawm kev siv tshuaj, μ g; W yog tus qauv kom muaj nuj nqis ntawm cov ntawv xeem, g; N yog qhov dilution piv ntawm cov qauv kuaj.

3. Raws li cov xwm txheej saum toj no, nws tuaj yeem ua rau lub hydrolysis ntawm hemoglobin los tsim 1 μ Cov enzyme kom muaj nuj nqis ntawm mol tyrosine yog ib chav ua haujlwm protease.

6.IR: KBr disc

7. Kev ruaj ntseg thiab kev nyab xeeb

Kev ruaj ntseg:

Nyob ruaj khov nyob rau hauv cov xwm txheej zoo (chav kub). Cov Ntaub Ntawv Kev ruaj ntseg muaj nyob rau ntawm koj qhov kev thov.
Kev nyab xeeb:

Raws li GARS (Feem ntau Pom Zoo Raws Li Kev Nyab Xeeb) Daim Ntawv Ceeb Toom ntawm Teb Chaws Asmeskas, nws muaj kev nyab xeeb rau tib neeg noj.

8. Flow Chart

9. Cov neeg siv lus pom

Peb muaj cov khw muag khoom ntawm Alibaba, Chemicalbook thiab LookChem, los ntawm cov khoom lag luam zoo thiab cov kev pabcuam tsis tau txais kev pabcuam, peb tau txais ntau cov lus pom zoo.

10.Peb Cov Ntawv Pov Thawj

Tau ntau xyoo, peb tau cog lus rau cov khoom tsim khoom optimization thiab kev tsim kom zoo. Peb tau teeb tsa qhov kev tswj hwm zoo thiab tau txais daim ntawv pov thawj ntawm nws.

11.Peb cov neeg muas zaub

Peb tau tsim kev lag luam kev sib raug zoo nrog Abbott, Unilever, Shiseido, KANS thiab SIMM, thiab lwm yam.

12. Exhibitions

Peb feem ntau tuaj koom kev nthuav qhia thoob ntiaj teb, suav nrog CPhI, FIC, API, Vitafoods, SupplesideWest.

Cim npe nrov: pepsin 9001-75-6, manufacturers, lwm tus neeg, Hoobkas, lag luam wholesale, yuav, nqe, zoo tshaj plaws, tej, kev muag khoom