D-Ribose

​1.InRoduction
D-Ribose yog tsib-carbon aldose nrog cov tshuaj noj cov mis nyuj c₅h₁₀o₅ thiab yog ib qho tseem ceeb ntawm cov roj ntsha roj acid (RNA) Nws muaj nyob hauv cov nroj tsuag thiab tsiaj hlwb, thiab tseem yog tus tseem ceeb ua ntej rau cov khoom siv nucleoseside, nrog cov ntawv thov tseem ceeb hauv cov tshuaj, khoom noj thiab lwm daim teb.

2.Yam ua hauj lwm
D-ribose muaj cov haujlwm tseem ceeb hauv cov muaj sia muaj sia: raws li kev sib xyaw ntawm RNA, nws yog koom nrog hauv kev kis cov ntaub ntawv ntsig txog caj ces; Nws yog lub hauv paus qauv ntawm lub zog xws li ATP, uas ua rau muaj peev xwm ntawm lub zog ntawm tes; Nws kuj tseem tuaj yeem synthesibe nucleoside analogues (piv txwv li, coenzymes, nucleotides, thiab yog qhov tseem ceeb rau lub neej ua si.

3.Applications

D-ribose yog qhov tseem ceeb ntawm RNA, koom nrog kev sib kis cov ntaub ntawv keeb kwm, tab sis lwm yam ntaub so ntswg, txhim kho cov ntaub ntawv hluav taws xob thiab lwm yam ntaub so ntswg thiab tiv thaiv kev qaug zog.
D-Ribose Muaj ntau cov ntawv thov: Nws yog siv nyob rau hauv synthesis ntawm cov tshuaj nucleoside thiab cov hlab ntsha thiab cov cerebrovascular kev noj qab haus huv cov khoom lag luam hauv chaw muag tshuaj; Nws yog siv los ua cov khoom qab zib thiab muaj txiaj ntsig zoo hauv kev lag luam khoom noj; Nws yog siv los txhim kho cov metabolism thiab kev tiv thaiv ntawm cov tsiaj hauv kev lag luam pub, thiab nws lub peev xwm yuav txuas ntxiv mus ntxiv.

4.flow daim ntawv

5.Qhov xwm txheej ntawmFluconazole

6.MethoD of kev ntsuas ntawmFluconazole

Tom qab pretreaticment, cov qauv tau kuaj pom los ntawm cov kab ntawv ametonitrile-dej (75:25, {} ml \/ min thiab ib qho kev ntsuas oscillometric. Lub sijhawm ua haujlwm tau muab piv nrog tus qauv rau kev txheeb xyuas cov kev tsim nyog, thiab cov ntsiab lus tau suav los ntawm cov qauv kev ntsuas sab nraud, uas haum rau cov khoom noj khoom haus ntawm D-Ribose hauv cov zaub mov thiab tshuaj.

Txoj kev 2: nyias txheej chromatography (TLC)
Hnov cov piv txwv daws teeb meem ntawm silica gel g nyias txheej pwb, tom qab extroldic acider, thiab tom qab ntawd rhuab ntawm 105 degree kom txog thaum cov pob muaj xim. Tus nqi RF ntawm qhov chaw tau muab piv nrog tus qauv rau kev txheeb xyuas kev ua kom zoo, uas haum rau kev soj ntsuam ua ntej lossis kev soj ntsuam ib nrab.

Qauv 3: Kev Tshawb Xyuas Enzymatic
Siv D-Ribose isomerase kom tshwj xeeb cataling ntawm d-ribose tshwm sim ntawm d-rible, thiab tom qab kom pom cov khoom siv ntawm d-aws

7.Siv DROMULALOrAM NTAWM D-Ribose siv tshuaj

8.Ruaj khov thiab kev nyab xeeb
Stability:
Ruaj khov nyob rau hauv cov xwm txheej (chav sov). Muaj cov ntaub ntawv ruaj khov yog muaj raws li koj qhov kev thov.
Kev Nyab Xeeb:
Raws li Gars (feem ntau lees paub tias muaj kev nyab xeeb) tsab ntawv ceeb toom ntawm peb, nws muaj kev nyab xeeb rau tib neeg kev noj haus.

9.Customer lus

Peb muaj khw ntawm Alibaba, Cov Lus Qhia thiab saib xyuas cov khoom lag luam zoo thiab tsis muaj kev pab cuam zoo, peb tau txais ntau cov lus zoo.

10.our daim ntawv pov thawj

Tau ntau xyoo, peb tau mob siab rau cov khoom lag luam tsim thiab tsim cov kev tsim kom zoo. Peb tau teeb tsa cov txheej txheem tswj hwm zoo thiab tau txais cov ntawv pov thawj ntawm nws.

11.our cov neeg siv khoom

Peb tau tsim kev sib raug zoo nrog Abbott, Unilever, Shisido, Kans thiab Simm, thiab lwm yam.

12.exhhiouss

Peb feem ntau tuaj koom cov neeg ua yeeb yam thoob ntiaj teb, suav nrog CPHI, FIC, API, Vitafoods, txhawb nqa.

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Cim npe nrov: D-Ribose, Tuam Tshoj D-Ribose Cov Chaw Tsim Khoom, Chaw muag khoom, Hoobkas