Ceratonia Siliqua Extract CAS 643-12-9

1. Taw qhia
Ceratonia siliqua yog lub npe botanical ntawm Carob, ib hom taum khawv koob los ntawm ntug dej hiav txwv Mediterranean. Yog vim li cas nws yog tej yam yees siv? Vim hais tias txhua cov hlaws ntawm nws cov noob hnyav txog 0.2g, txoj cai, nws yog lub hauv paus chiv keeb ntawm lub ntiaj teb pob zeb diamond hnyav tus qauv "Carat" (Carob). Tsis tas li ntawd, ceratonia siliqua extract muaj cov khoom tseem ceeb uas muaj cov haujlwm tshwj xeeb, cov khoom xyaw no yog D-chiro Inositol (tseem hu ua DCI). DCI belongs rau tsev neeg vitamin B, tseem hu ua vitamin B8. Nws yog tib neeg cov metabolite uas muaj cov haujlwm tshwj xeeb ntawm lub cev xws li tswj hwm hormonal tshuav, kev coj khaub ncaws tsis zoo thiab kev tso tawm insulin. Nws txoj kev ua tau zoo tau raug pov thawj hauv tebchaws Europe thiab Tebchaws Meskas.

2. Lub luag haujlwm tseem ceeb
2.1. Regulating hormonal tshuav nyiaj li cas thiab txhim kho poj niam physiological teeb meem thiab pob txuv
Nws paub zoo tias cov tshuaj hormones hauv tib neeg lub cev tseem ceeb heev vim lawv txiav txim siab kev loj hlob, kev loj hlob thiab cov metabolism hauv lub cev.
Lub hypothalamus secretes gonadotropin-tso cov tshuaj hormones, uas ua rau lub caj pas pituitary. Lub caj pas pituitary secretes gonadotropins, suav nrog folliculopoietin thiab luteinising hormone, uas ua rau zes qe menyuam. Lub zes qe menyuam tsim cov tshuaj estrogen thiab progesterone, uas ua rau lub tsev menyuam tsim kev coj khaub ncaws txhua hli. Txoj cai tswj kev coj khaub ncaws no yog hu ua HPO axis. Nyob rau hauv no mechanism ntawm poj niam cev xeeb tub regulator, lub HPO axish, tus thawj coj yog lub hypothalamus thiab lub tsev menyuam yog cov executor tshwj xeeb. Cov txheej txheem los ntawm tus thawj coj cov lus qhia mus rau tus thawj coj lub txais tos yuav tsum tau ib tug thauj, thiab D-chiral inositol (Ceratonia Siliqua Extract) yog zoo li cov roj rau no transporter.
DCI tswj cov qib tshuaj hormones los ntawm kev tswj cov qib ntawm kev sib deev hormone khi cov proteins, thiab kev coj khaub ncaws tuaj yeem rov qab tau thaum cov tshuaj hormones zoo li qub thiab zes qe menyuam zais cov tshuaj hormones kev sib deev ib txwm.
DCI muaj txiaj ntsig zoo hauv kev txhim kho lub cev lub cev thiab pob txuv hauv cov poj niam nrog PCOS

58 tus poj niam nrog PCOS, (hnub nyoog 27 ± 7)
250 mg DCI plus Mn plus folic acid plus Vit. B12; 12 lub lis piam ntawm kev noj tshuaj tas mus li

Qhov tshwm sim:
- Txhim kho physiological voj voog
- Kev txo qis hauv basal insulin thiab triglyceride hauv cov ntshav

Txhim kho Ovulation Function
DCI muaj txiaj ntsig zoo hauv kev txhim kho ovulatory muaj nuj nqi, hormonal ntshawv siab thiab metabolic syndrome hauv cov poj niam rog.

44 poj niam rog
1,200 mg (raws li DCI) / hnub rau 6 mus rau 8 lub lis piam

Qhov tshwm sim:

Hauv pawg DCI, insulin rhiab heev tau nce thiab ovulatory muaj nuj nqi tau txhim kho hauv cov neeg mob PCOS (ovulation tus nqi: 86 feem pua ​​​​hauv DCI vs. 27 feem pua ​​​​hauv cov placebo pawg).
Hauv pawg DCI, intra-serum dawb testosterone, androgens, ntshav siab thiab nruab nrab rog tau qis dua.

DCI muaj txiaj ntsig zoo hauv kev txhim kho ovulatory muaj nuj nqi, hormonal ntshawv siab thiab metabolic syndrome hauv cov poj niam slim

20 tus poj niam slim
600 mg (raws li DCI) / hnub rau 8 lub lis piam

Qhov tshwm sim:
Ovulation tus nqi: 60 feem pua ​​​​hauv DCI pawg vs. 20 feem pua ​​​​hauv cov placebo

2.2 Txhim kho cov tshuaj insulin, txhim kho insulin tsis kam, thiab txhim kho cov tsos mob polycystic
Thaum D-chiral inositol (Ceratonia Siliqua Extract) tsis txaus, nws nyuaj rau lub cev kom metabolize qab zib kom zoo thiab yuav ua rau cov tshuaj insulin siab, uas txhais tau hais tias lub zes qe menyuam tseem tsim testosterone. d-chiral inositol tswj cov kev taw qhia cov tshuaj insulin, txhim kho insulin rhiab heev, tswj cov piam thaj metabolism thiab txhawb nqa glycogen synthesis, yog li txhim kho insulin tsis kam, txo cov qib androgen siab thiab txhim kho cov tsos mob ntawm polycystic zes qe menyuam syndrome xws li ovulation txawv txav.

Kev noj DCI txo qis metabolic syndrome los ntawm kev txo qis insulin tsis kam

Kev sim tshuaj ntsuam xyuas kev siv DCI hauv kev xeeb tub ntshav qab zib
Kev sim.
-Cov neeg mob ntshav qab zib gestational ntawm 24-28 lub lis piam ntawm cev xeeb tub (txhais tau tias muaj hnub nyoog txog 27 xyoo, BMI 20-21)
-OGTT 1) Glucose 5.1 mmol / L ua ntej noj cov piam thaj (fasting); qabzib 10.0 mmol / L 1 teev tom qab noj cov piam thaj thiab 8.5 mmol / L lossis ntau dua 2 teev tom qab noj cov piam thaj tuaj yeem kuaj pom tias yog ntshav qab zib gestational.

Pab pawg ntawm cov kev xeem xeem thiab cov txheej txheem ntawm kev tswj hwm.
- Tus naj npawb ntawm cov neeg: 80 nyob rau hauv tag nrho
- Lub sijhawm ua haujlwm: 8 lub lis piam
1) Pawg A: Pab pawg tswj hwm (folic acid 400ug / d)
2) Pab pawg B: Myo-inositol (MI) pawg (MI 3,000 mg/d)
3) Pawg C: D-chiro-inositol pawg (DCI) (DCI 500mg / d)
4) Pawg D: MI ntxiv rau DCI pawg (6: 1; 3, 000mg ntxiv rau 500mg / d)

Cov txiaj ntsig sim:
Postprandial qabzib, glycosylated hemoglobin1), yoo mov insulin, tag nrho cov roj cholesterol, thiab cov rog nruab nrab tau txo qis hauv MI, DCI, thiab MI ntxiv rau DCI pawg piv nrog pawg tswj hwm (p<0.05), and statistically more significantly reduced in the DCI and MI+DCI groups compared with the MI group (p<0.05)

Cov txiaj ntsig:
Glycosylated hemoglobin (HbA1c): lub conjugate ntawm hemoglobin thiab qabzib hauv cov qe ntshav liab, uas pab thauj cov piam thaj; nws yog ib qho kev ntsuas los xyuas cov ntshav qabzib mus ntev (cov ntshav qab zib) cov ntsiab lus, nrog rau tus nqi ib txwm yog 4-5.9 feem pua.

HOMA-IR1) thiab HOMA-I SI2) tau txo qis lossis nce hauv MI, DCI, thiab MI ntxiv rau pawg DCI piv rau pawg tswj hwm (p<0.05)
Kev txheeb xyuas qhov txo qis hauv DCI thiab MI ntxiv rau DCI pawg piv rau MI pawg

3. Cov ntawv thov
Ceratonia siliqua extract yog mianly siv hauv cov khoom kho mob.

4. Flow Chart
Carob raw khoom → Carob syrup → Kub extraction → Tshwj xeeb extraction → Chromatography → Crystalization → Cov khoom tiav

5. Tus Qauv Zoo

Raws li Enterprise Standard

6. Txoj kev tsom xam

MOA muaj nyob rau thaum thov.

7. Reference Spectrum

8. Kev ruaj ntseg thiab kev nyab xeeb

Kev ruaj ntseg:

Nyob ruaj khov nyob rau hauv cov xwm txheej zoo (chav kub). Cov Ntaub Ntawv Kev ruaj ntseg muaj nyob rau ntawm koj qhov kev thov.
Kev nyab xeeb:

Raws li GARS (Feem ntau Pom Zoo Raws Li Kev Nyab Xeeb) Daim Ntawv Ceeb Toom ntawm Teb Chaws Asmeskas, nws muaj kev nyab xeeb rau tib neeg siv.

9. Cov neeg siv lus pom

10. Peb Daim Ntawv Pov Thawj

11. Peb Cov Neeg Siv Khoom

12. Exhibition

Cim npe nrov: ceratonia siliqua extract cas 643-12-9, manufacturers, lwm tus neeg, Hoobkas, lag luam wholesale, yuav, nqe, zoo tshaj plaws, tej, kev muag khoom