Ferulic acid hmoov yog thawj zaug cais nyob rau hauv thaum ntxov 19th caug xyoo los ntawm cov nplej bran. Nws yog thawj zaug piav raws li cov khoom siv crystalline daj uas muaj qhov tsw qab. Lub sijhawm ntawd, nws cov qauv tshuaj tsis tau nkag siab tag nrho, thiab nws cov kev siv tau tseem tsis tau paub.
Nws tsis yog txog thaum xyoo pua 20th uas cov kws tshawb fawb tau pib tshawb nrhiav cov txiaj ntsig kev noj qab haus huv ntawm ferulic acid. Hauv xyoo 1989, nws tau tshawb pom tias ferulic acid muaj cov khoom muaj zog antioxidant, uas ua rau muaj ntau yam kev tshawb fawb tshawb nrhiav nws lub luag haujlwm hauv kev noj qab haus huv plawv, tiv thaiv qog noj ntshav, thiab tiv thaiv tawv nqaij.
Ferulic acid hmoov muaj nyob rau hauv ntau yam ntawm cov nroj tsuag. Qee qhov chaw tshaj plaws ntawm ferulic acid suav nrog mov, nplej, oats, thiab barley. Ferulic acid kuj muaj nyob rau hauv ntau cov txiv hmab txiv ntoo thiab zaub, nrog rau txiv kab ntxwv, txiv apples, txiv lws suav, thiab carrots.
Tsis tas li ntawd, ferulic acid yog ib qho tseem ceeb ntawm ntau cov tshuaj ntsuab tshuaj, xws li Angelica sinensis, Ligusticum chuanxiong, thiab Scutellaria baicalensis. Ferulic acid kuj muaj nyob rau hauv ntau yam txuj lom, xws li cinnamon, cumin, thiab cardamom.
Kev ua haujlwm ntawm ferulic acid:
Ferulic acid muaj ntau yam txiaj ntsig kev noj qab haus huv vim nws cov tshuaj tua kab mob antioxidant thiab tiv thaiv kab mob. Antioxidants yog cov khoom tseem ceeb uas tiv thaiv cov hlwb los ntawm kev puas tsuaj los ntawm cov dawb radicals. Cov dawb radicals yog cov molecules uas tuaj yeem ua rau cov hlwb puas tsuaj, ua rau muaj cov kab mob ntev xws li mob qog noj ntshav, kab mob plawv, thiab Alzheimer's disease.
Tsis tas li ntawd, ferulic acid muaj cov tshuaj tiv thaiv kab mob, uas ua lub luag haujlwm tseem ceeb hauv kev txo qis kev pheej hmoo ntawm cov kab mob ntev, xws li mob caj dab, ntshav qab zib, thiab metabolic syndrome.
Ferulic acid kuj tseem ua lub luag haujlwm hauv kev tiv thaiv tawv nqaij los ntawm kev txo qhov kev puas tsuaj los ntawm UV hluav taws xob. Cov kev tshawb fawb tsis ntev los no tau pom tias ferulic acid tuaj yeem hais txog ntau yam kev txhawj xeeb ntawm daim tawv nqaij, suav nrog wrinkles, hnub nyoog me ntsis, thiab kev hloov ntawm daim tawv nqaij.
Ferulic acid muaj ntau nyob rau hauv ntau cov txiv hmab txiv ntoo, zaub, thiab nplej, ua rau nws siv tau los ntawm kev noj qab haus huv. Ntau cov kev tshawb fawb tau pom tias kev noj cov zaub mov uas muaj ferulic acid tuaj yeem muab ntau yam txiaj ntsig kev noj qab haus huv, suav nrog txo kev pheej hmoo ntawm cov kab mob ntev xws li kab mob plawv thiab qee hom mob qog noj ntshav.
Ferulic acid tsis ntev los no tau txais txiaj ntsig tseem ceeb hauv kev lag luam tshuaj pleev ib ce. Nws yog dav siv hauv cov khoom tu tawv nqaij vim nws muaj zog antioxidant thiab tiv thaiv tawv nqaij. Ferulic acid tuaj yeem txo qhov kev pheej hmoo ntawm cov tawv nqaij puas tsuaj los ntawm cov dawb radicals, UV hluav taws xob, thiab ib puag ncig muaj kuab paug, ua rau nws yog ib qho tseem ceeb ntawm ntau cov tshuaj pleev ib ce.
Txoj kev tsim cov nroj tsuag ferulic acid feem ntau suav nrog cov hauv qab no:
1. Kev rho tawm los ntawm cov phab ntsa ntawm cov nroj tsuag: Ferulic acid feem ntau cuam tshuam nrog polysaccharides thiab lignin los ntawm ester bonds, los yog undergoes tus kheej esterification los yog etherification los tsim ferulic acid. Feem ntau, alkaline thiab enzymatic txoj kev yog siv los rhuav tshem ester bonds thiab tso ferulic acid, ua raws li los ntawm extraction siv cov kuab tshuaj tsim nyog. Piv txwv li, siv 4% sodium hydroxide kom hnov mob hauv chav tsev kub hauv qab nitrogen rau 24 teev tuaj yeem tso ferulic acid 1 los ntawm phab ntsa ntawm tes.
2. Extraction los ntawm cov ntaub so ntswg: Ferulic acid yog dav nyob rau hauv cov nroj tsuag lub nceeg vaj, tshwj xeeb tshaj yog nyob rau hauv cov noob thiab nplooj ntawm cov nroj tsuag. Piv txwv li, Ferula foetida regei yog ib qho tseem ceeb ntawm ferulic acid. Lwm cov nroj tsuag uas muaj ferulic acid suav nrog ferulic acid, Ligusticum chuanxiong, Angelica sinensis, Cimicifuga elata, thiab Schisandra chinensis.
3. Kev siv tshuaj lom neeg: Txawm hais tias cov nroj tsuag yog lub hauv paus tseem ceeb ntawm ferulic acid, nws tseem tuaj yeem npaj los ntawm cov tshuaj synthesis. Piv txwv li, ferulic acid tuaj yeem npaj tau los ntawm hydrolyzing glutathione, uas yooj yim rau kev khiav lag luam thiab yields txog 85.7%.
Extraction txheej txheem ntawm ferulic acid:
1. Kev kho ua ntej: Sib tsoo thiab ntub cov ntaub ntawv cog kom zoo dua tso ferulic acid.
Extraction: Siv alkaline los yog enzymatic txoj kev ua txhaum ester bonds thiab tso ferulic acid. Feem ntau siv alkali yog sodium hydroxide, thiab cov txheej txheem enzymatic siv cov enzymes tshwj xeeb.
3 Purification: Tom qab rho tawm ferulic acid nrog cov kuab tshuaj tsim nyog, kev lim dej ntxiv yuav tsim nyog, xws li siv cov pa roj carbon activated kom tshem tawm cov impurities.
4 Kev sib cais: Thaum kawg, cov khoom lag luam ntshiab ferulic acid tau txais los ntawm cov kauj ruam xws li kev sib cais thiab ziab.
Yolanda
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