Keratosis pilaris, feem ntau hu ua nqaij qaib, tseem hu ua lichen pilaris lossis keratosis pilaris, yog kab mob ntawm daim tawv nqaij uas tshwm sim los ntawm qhov txawv txav infundibulum keratosis.
Keratosis pilaris yog tus cwj pwm los ntawm grey-xim av angular plugs nyob rau hauv funnel-puab pores, los yog tsaus liab keratinizing papules raws li lub pores, muaj frizzy plaub hau, thiab feem ntau nrog erythema thiab hyperpigmentation ntawm lub follicle qhib. Tus kab mob no tshwm sim ntawm lub ntsej muag, extensor sab ntawm caj npab, scapula thiab pob tw, feem ntau yog thaum yau, thiab muaj qhov tshwm sim ntau tshaj plaws thaum hluas. High concentration ntawm glycolic acid tuaj yeem kho qhov txawv txav keratinization ntawm cov plaub hau follicle duct orifice thiab tshem tawm cov keratinocytes ntau dhau; Nyob rau tib lub sijhawm, nws tuaj yeem txhawb cov tawv nqaij metabolism thiab ua kom cov metabolism ntawm melanin hais.
Muaj ib qho kev sim nyob rau hauv uas siab concentrationsglycolic acid zogtau siv los kho keratosis pilaris.
25 tus neeg kawm tau xaiv thaj chaw uas muaj cov kab mob ntawm daim tawv nqaij, siv cov concentration ntawm glycolic acid sib npaug ntawm qhov chaw kuaj, rov kho dua ib zaug txhua 20 hnub, tag nrho 4 zaug, thiab kho cov neeg mob ntawm 20th, 40th, 60th, thiab 80th. hnub raws li. Cov keratinizing papules ntawm cov hauv paus hniav raug suav, erythema thiab xim xim ntawm lub qhov ncauj follicle raug ntsuas, thiab ntsuas kev ua tau zoo thiab kev nyab xeeb.
Tus naj npawb ntawm keratotic papules ntawm follicular orifice tau suav, thiab cov naj npawb ntawm keratotic papules ntawm follicular orifice tuaj yeem pom kom txo qis nrog kev nce ntawm cov kev kho mob. Paired t test tau ua tiav ntawm tus naj npawb ntawm keratinizing papules ua ntej thiab tom qab kev kho mob, thiab muaj qhov sib txawv tseem ceeb ntawm kev txo qis keratinizing papules rau hnub 20, 40, 60 thiab 80 (P<0.05) (fig.="">
Ua ntej kev kho mob, nyob rau 20th hnub ntawm kev kho mob, 40th hnub ntawm kev kho mob, 60th hnub ntawm kev kho mob, thiab 80th hnub ntawm kev kho mob, cov tawv nqaij melanin thiab hemoglobin testers tau siv los ntsuas M tus nqi thiab E tus nqi ntawm qhov qhib ntawm lub cov plaub hau follicle ntawm qhov kev kawm qhov chaw xeem, feem. L tus nqi yog ntsuas los ntawm ib qho spectrophotometer, thiab qhov nruab nrab tus nqi ntawm 3 kev ntsuas tau coj txhua lub sijhawm thiab suav nrog cov txheeb cais. Tus nqi M ntawm 40, 60 thiab 80 hnub tom qab kev kho mob yog qhov txawv ntawm M tus nqi ua ntej kev kho mob (P<0.05); the="" difference="" was="" statistically="" significant=""><0.05); the="" l*="" value="" on="" the="" 40th,="" 60th="" and="" 80th="" days="" after="" treatment="" was="" significantly="" different="" from="" that="" before="" treatment=""><>
Thaum lub sij hawm tag nrho cov txheej txheem soj ntsuam, tsis muaj cov ntsiab lus poob, thiab cov neeg kawm tau zam qhov siab ntawm glycolic acid zoo. Tsuas yog ib tus neeg tau ntsib kev kub hnyiab, khaus thiab tsis xis nyob thaum kho nrog 70 feem pua glycolic acid, thiab cov tsos mob tau ua raws li hauv qab no: Nws ploj mus tom qab kev siv tshuaj nruab nrab, thiab tsis muaj qhov hnov tsw, tawv nqaij rhiab thiab khawb tom qab ua haujlwm.
Keratosis pilaris yog ib hom kab mob follicular keratotic tawv nqaij. Hauv kev kho mob ib txwm muaj, cov neeg uas muaj kab mob ntawm daim tawv nqaij tuaj yeem noj cov tshuaj vitamin A ntau ntawm qhov ncauj los txo cov tsos mob, tab sis kev siv mus ntev yuav ua rau muaj vitamin A lom; Cov tshuaj pleev retinoids kuj tuaj yeem siv los tswj thiab tswj cov keratinization ntawm keratinocytes, tab sispib yog qeeb. , cov neeg mob muaj kev ua tsis zoo, yooj yim rau rov qab, siv ntev ntawm daim tawv nqaij yuav tshwm sim erythema, desquamation thiab khaus, thiab lwm yam. Tam sim no, kev kho mob laser kuj tau siv dav hauv kev kho mob keratosis pilaris, tab sis feem ntau tsuas yog siv tau zoo. erythema thiab pigmentation nyob ib ncig ntawm lub hauv paus plaub hau. Cov plaub hau follicle papules tsis muaj txiaj ntsig. Tam sim no, tsis muaj laser uas tuaj yeem kho papules, erythema thiab hyperpigmentation ntawm keratosis pilaris tib lub sijhawm, thiab muaj qhov tsis zoo xws li qhov mob pom tseeb, lub sijhawm rov qab los ntev,tus nqi siab thiab lub sijhawm kho mob ntev.
Glycolic acid yog qhov tsawg tshaj plaws molecular hnyav txiv hmab txiv ntoo acid, tseem hu ua glycolic acid. Glycolic acid hmoov yog cov kua qaub uas tsis muaj zog uas tsis ua rau cov tawv nqaij ua haujlwm tsis zoo, tuaj yeem cuam tshuam nrog kev sib khi ntawm lub xovtooj ntawm tes, txo cov adhesion thiab keratinocyte tsub zuj zuj ntawm keratinocytes, ua kom rov ua dua tshiab thiab tshem tawm ntawm cov kab mob epidermal, ua kom cov kua dej ntws tawm. infundibulum ntawm cov plaub hau follicle, thiab txo pigmentation. , thiab txhawb nqa collagen ntau lawm kom cov tawv nqaij noo noo thiab ci tawv nqaij.
Flavia
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