1. Taw qhia

Ecdysone Powder yog cov tshuaj steroid loj hauv cov kab thiab ua lub luag haujlwm tseem ceeb hauv kev sib koom ua ke kev loj hlob xws li larval molting thiab metamorphosis los ntawm nws cov metabolite active 20-hydroxyecdysone (20E). Nws yog ib qho khoom siv tau muab rho tawm los ntawm cov hauv paus hniav ntawm Cyanotis Arachnoidea CB Clarke, pearl dew cog ntawm tsev neeg Plantariaceae.Raws li cov purity ntawm txawv dawb, grey dawb, lub teeb daj los yog lub teeb xim av crystalline hmoov.Nws cov nyhuv ntawm tib neeg lub cev muaj peev xwm txhawb collagen synthesis, anti-arrhythmia, tiv thaiv qaug zog; txhawb kev loj hlob ntawm tes, txhawb nqa kev faib tawm ntawm tes, tshem tawm cov roj cholesterol hauv lub cev; txo cov ntshav lipids, inhibit qhov nce ntawm cov ntshav qab zib; qhib meridians, dehumidification thiab analgesia, thiab lwm yam physiological kev ua ub no. Nws yog ib tug natural anticancer agent.

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2. Muaj nuj nqi

2.1 Ecdysone hmoov txhawb cov synthesis ntawm nucleic acid thiab protein.

2.2 Txhawb lipid metabolism. Kev tswj hwm ntawm lipid metabolism yog cuam tshuam nrog cov nyhuv ntawm molting sterones ntawm cAMP- protein kinase system.

2.3 Kev ua haujlwm ntawm cov khoom siv raw rau cov tshuaj pleev ib ce:

Kev ua haujlwm ntawm ecdysone ua raw khoom rau tshuaj pleev ib ce:

Ua ntej tshaj plaws, nws tuaj yeem ua rau cov tawv nqaij softer, khaws cov dej noo, thiab txhawb kev loj hlob ntawm daim tawv nqaij monocytes thiab mucosal elastin, yog li ua si cov nyhuv ntawm anti-oxidation thiab moisturizing. Thib ob, lub ntsiab lus muaj cov txiaj ntsig zoo antioxidant, uas tuaj yeem tshem tawm cov oxidation ntau dhau hauv cov dawb radicals, tiv thaiv kev puas tsuaj ntawm cov pa oxygen reactive rau ntawm daim tawv nqaij molecules, txhawb kev tsim kho ntawm daim tawv nqaij epithelial hlwb thiab txo cov kab ntawm daim tawv nqaij laus.
Tsis tas li ntawd, nws kuj muaj qhov tseem ceeb los tiv thaiv kev ua xua, uas tuaj yeem tiv thaiv daim tawv nqaij los ntawm cov stimulants sab nraud. Los ntawm kev tiv thaiv ntawm daim tawv nqaij los ntawm kev puas tsuaj los ntawm kev tsis haum tshuaj, nws tseem tuaj yeem ua si cov teebmeem ntawm kev tiv thaiv rhiab heev, txo qhov liab thiab o, tiv thaiv daim tawv nqaij thiab lwm yam. Thaum kawg, molting hormone kuj tuaj yeem cuam tshuam cov androgen hauv daim tawv nqaij, txo cov roj tawm ntawm daim tawv nqaij, thiab ua kom cov tawv nqaij du thiab moist. Yog li ntawd, kev siv ecdysone hauv cov khoom siv tshuaj pleev ib ce yog qhov tseem ceeb tshwj xeeb.
Ecdysone tuaj yeem siv rau hauv txhua hom tshuaj pleev ib ce, suav nrog tshuaj pleev, tshuaj pleev ib ce, tshuaj pleev, tshuaj pleev ntsej muag thiab tshuaj pleev thaiv hnub. Vim nws txoj kev nyab xeeb zoo, tsis ua rau khaus thiab ua haujlwm zoo ntawm kev kho tawv nqaij, nws yog ntau thiab ntau dua siv hauv tshuaj pleev ib ce. Yog li ntawd, kev saib xyuas zoo tau raug them rau nws daim ntawv thov hauv cov khoom siv tshuaj pleev ib ce.
Txhawm rau ua kom tiav, ecdysone muaj ntau yam haujlwm, tiv thaiv daim tawv nqaij zoo, tiv thaiv kev laus ntawm daim tawv nqaij, txo cov roj ntawm daim tawv nqaij, thiab muaj zog tiv thaiv kev ua xua thiab antioxidant zog, yog li nws tau siv dav hauv cov khoom siv tshuaj pleev ib ce. Nws tseem yuav ua lub luag haujlwm tseem ceeb hauv kev pab cov neeg siv khoom kom ua tiav cov tawv nqaij noj qab haus huv thiab zoo nkauj yav tom ntej.

2.4 Immunomodulatory nyhuv. Cov nyhuv inhibitory ntawm histamine tso tawm los ntawm nas peritoneal mast hlwb yuav cuam tshuam rau nws cov nyhuv inhibitory ntawm kev mobilization ntawm intracellular calcium cia.

ua rau PGRP-LC qhia tswj Drosophila innate tiv thaiv|EMBO Journal.

Ecdysone Functions

3. Daim ntawv thov

Ecdysone Powder feem ntau yog siv hauv kev lag luam tshuaj, khoom siv kho mob.

Ecdysone Applications (1)

Specifications

Yam khoom	SPECIFICATIONS
Ecdysterone cov ntsiab lus	Ntau dua lossis sib npaug rau 98.00 feem pua
Txoj kev tshuaj xyuas	HPLC
Ib feem siv	Tshuaj ntsuab
Qhov tshwm sim	Crystal hmoov
Xim	Dawb
tsw	Yam ntxwv
Saj	Yam ntxwv
Poob rau ziab	Tsawg dua lossis sib npaug li 5.0 feem pua
Residue ntawm Ignition	Tsawg dua los yog sib npaug rau 1.0 feem pua
Raws li	Tsawg dua lossis sib npaug li 5ppm
Pb	Tsawg dua lossis sib npaug li 2ppm
Cd	Tsawg dua lossis sib npaug li 1ppm
Hg	Tsawg dua los yog sib npaug rau 0.5ppm
Tag Nrho Phaj suav	Tsawg dua lossis sib npaug li 1000cfu / g
Total Poov & Pwm	Tsawg dua lossis sib npaug li 100cfu / g
E. Coli.	Tsis zoo
Salmonelia	Tsis zoo
Staphylococcus	Tsis zoo

4.Flow chart

6. Kev xeem

B.1 Kev txiav txim siab ntawm ecdysone (HPLC)

B.1.1 Reagents thiab cov ntaub ntawv

B.1.1.1 Acetonitrile: chromatographically ntshiab

B.1.1.2 Deionized dej

B.1.1.3 Lim: 0.45μm

B.1.1.4 -ecdysone tswj tshuaj

B.1.2 Cov cuab yeej thiab cov cuab yeej siv

B.1.2.1 Kev ua haujlwm siab ua kua chromatography

B.1.3 Siv cov xwm txheej chromatographic

B.1.3.1 Chromatographic kem: chromatographic kem nrog octadecylsilane bonded silica gel ua muab tub lim

B.1.3.2 Mobile theem: acetonitrile-water=15:85

B.1.3.3 Kev Ntsuas wavelength: 242nm

B.1.3.4 Tus nqi ntws: 1.0ml/min

B.1.3.5 Kem kub: 35 degree

B.1.4 Cov kauj ruam tsom xam

Kev npaj ntawm kev siv tshuaj: noj ib qho tsim nyog ntawm -ecdysone siv cov khoom siv, ntsuas kom raug, muab tso rau hauv lub raj mis ntsuas, ntxiv cov theem txawb los ua cov tshuaj uas muaj 0.2 mg ntawm -ecdysone ib 1ml, thiab co zoo.

Kev npaj cov tshuaj ntsuam xyuas: noj li 20mg (50 feem pua cov ntsiab lus) ntawm cov qauv mus kuaj, ntsuas kom raug, muab tso rau hauv 50ml ntsuas lub raj mis, ntxiv cov theem txawb kom yaj, dilute rau lub cim, thiab co zoo.

Kev txiav txim siab txoj kev: lim cov tshuaj siv thiab cov tshuaj ntsuam xyuas nrog rau 0.45μm lim membrane, feem, precisely kos 10ul thiab txhaj rau hauv cov kua chromatograph. Lub sijhawm khaws cia ntawm chromatographic ncov ntawm cov qauv yuav tsum ua raws li cov khoom siv siv. Ob qho piv txwv thiab cov ntaub ntawv siv tau raug sim ob zaug, thiab qhov nruab nrab qhov siab tshaj plaws tau txais thiab suav.

B.1.5 Cov txiaj ntsig suav

Qhov loj feem ntawm cov qauv ecdysone yog xam raws li formula (3):

test method …………………………(3)

——Concentration ntawm -ecdysone siv tshuaj, (mg / ml);

A1-- qhov nruab nrab chromatographic ncov cheeb tsam ntawm -ecdysone siv tshuaj;

A2-- qhov nruab nrab chromatographic ncov cheeb tsam ntawm tus qauv;

A3-- Qhov hnyav ntawm tus qauv, (mg).

7. HPLC

Ecdysone HPLC

8. Kev ruaj ntseg thiab kev nyab xeeb

Peb tau ua ntau yam kev ruaj ntseg thiab kev nyab xeeb kawm txog cov khoom no, raws li cov ntaub ntawv ceev ceev thiab kev ruaj ntseg mus sij hawm ntev, nws qhia cov yam ntxwv ruaj khov; raws li kev tshawb nrhiav tsiaj txhu, nws qhia tau tias muaj kev nyab xeeb.

9. Daim ntawv pov thawj

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